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Steven Fletcher

Showing results (71-80 of 112) with videos related to

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The Journal of Pharmacology and Experimental Therapeutics|October 28, 2020
Mechanistic Analysis of an Extracellular Signal-Regulated Kinase 2-Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative StressRamon Martinez, Weiliang Huang, Ramin Samadani, et al.
Organic & Biomolecular Chemistry|March 8, 2012
Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitorsJeremy L Yap, Xiaobo Cao, Kenno Vanommeslaeghe, et al.
Bioorganic & Medicinal Chemistry Letters|November 29, 2016
Synthesis, characterization and antineoplastic activity of bis-aziridinyl dimeric naphthoquinone - A novel class of compounds with potent activity against acute myeloid leukemia cellsBrandon A Carter-Cooper, Steven Fletcher, Dana Ferraris, et al.
Chemical Communications (Cambridge, England)|January 29, 2010
Coordination complex SH2 domain proteomimetics: an alternative approach to disrupting oncogenic protein-protein interactionsJoel A Drewry, Steven Fletcher, Peibin Yue, et al.
Angewandte Chemie (International Ed. in English)|July 2, 2011
Artificially induced protein-membrane anchorage with cholesterol-based recognition agents as a new therapeutic conceptMiriam Avadisian, Steven Fletcher, Baoxu Liu, et al.
Journal of Medicinal Chemistry|December 14, 2011
Small molecule STAT5-SH2 domain inhibitors exhibit potent antileukemia activityBrent D G Page, Haytham Khoury, Rob C Laister, et al.
ACS Medicinal Chemistry Letters|January 14, 2026
First-in-Class Potent, Dual HDAC6/Proteasome Inhibitors Lacking a Hydroxamic Acid Motif: Discovery of Novel Anti-Multiple Myeloma AgentsAlexandria M Chan, Brandon D Lowe, Andrea L Cottingham, et al.
Chembiochem : a European Journal of Chemical Biology|August 1, 2009
Disruption of transcriptionally active Stat3 dimers with non-phosphorylated, salicylic acid-based small molecules: potent in vitro and tumor cell activitiesSteven Fletcher, Jagdeep Singh, Xiaolei Zhang, et al.
BMC Cancer|November 23, 2012
The downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibitionChander Peddaboina, Daniel Jupiter, Steven Fletcher, et al.
Bioorganic & Medicinal Chemistry Letters|April 30, 2018
Kröhnke pyridines: Rapid and facile access to Mcl-1 inhibitorsIvie L Conlon, Daniel Van Eker, Sameh Abdelmalak, et al.
Pageof 12

Showing results (71-80 of 112) with videos related to

Sort By:
Pageof 12
The Journal of Pharmacology and Experimental Therapeutics|October 28, 2020
Mechanistic Analysis of an Extracellular Signal-Regulated Kinase 2-Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative StressRamon Martinez, Weiliang Huang, Ramin Samadani, et al.
Organic & Biomolecular Chemistry|March 8, 2012
Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitorsJeremy L Yap, Xiaobo Cao, Kenno Vanommeslaeghe, et al.
Bioorganic & Medicinal Chemistry Letters|November 29, 2016
Synthesis, characterization and antineoplastic activity of bis-aziridinyl dimeric naphthoquinone - A novel class of compounds with potent activity against acute myeloid leukemia cellsBrandon A Carter-Cooper, Steven Fletcher, Dana Ferraris, et al.
Chemical Communications (Cambridge, England)|January 29, 2010
Coordination complex SH2 domain proteomimetics: an alternative approach to disrupting oncogenic protein-protein interactionsJoel A Drewry, Steven Fletcher, Peibin Yue, et al.
Angewandte Chemie (International Ed. in English)|July 2, 2011
Artificially induced protein-membrane anchorage with cholesterol-based recognition agents as a new therapeutic conceptMiriam Avadisian, Steven Fletcher, Baoxu Liu, et al.
Journal of Medicinal Chemistry|December 14, 2011
Small molecule STAT5-SH2 domain inhibitors exhibit potent antileukemia activityBrent D G Page, Haytham Khoury, Rob C Laister, et al.
ACS Medicinal Chemistry Letters|January 14, 2026
First-in-Class Potent, Dual HDAC6/Proteasome Inhibitors Lacking a Hydroxamic Acid Motif: Discovery of Novel Anti-Multiple Myeloma AgentsAlexandria M Chan, Brandon D Lowe, Andrea L Cottingham, et al.
Chembiochem : a European Journal of Chemical Biology|August 1, 2009
Disruption of transcriptionally active Stat3 dimers with non-phosphorylated, salicylic acid-based small molecules: potent in vitro and tumor cell activitiesSteven Fletcher, Jagdeep Singh, Xiaolei Zhang, et al.
BMC Cancer|November 23, 2012
The downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibitionChander Peddaboina, Daniel Jupiter, Steven Fletcher, et al.
Bioorganic & Medicinal Chemistry Letters|April 30, 2018
Kröhnke pyridines: Rapid and facile access to Mcl-1 inhibitorsIvie L Conlon, Daniel Van Eker, Sameh Abdelmalak, et al.
Pageof 12