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Steven G Hughes

Showing results (1-10 of 32) with videos related to

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Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing|February 26, 2015
The effect of C-reactive protein reduction with a highly specific antisense oligonucleotide on atrial fibrillation assessed using beat-to-beat pacemaker Holter follow-upConn Sugihara, Nick Freemantle, Steven G Hughes, et al.
Arthritis Research & Therapy|April 18, 2015
Results of a proof of concept, double-blind, randomized trial of a second generation antisense oligonucleotide targeting high-sensitivity C-reactive protein (hs-CRP) in rheumatoid arthritisMarshelle S Warren, Steven G Hughes, Walter Singleton, et al.
Nucleic Acid Therapeutics|August 12, 2017
Lack of QT Prolongation for 2'-O-Methoxyethyl-Modified Antisense Oligonucleotides Based on Retrospective Exposure/Response Analysis of Ten Phase 1 Dose-Escalation Placebo-Controlled Studies in Healthy SubjectsRosie Z Yu, Rudy Gunawan, Richard S Geary, et al.
Journal of Clinical Lipidology|November 28, 2017
Temporal variability in lipoprotein(a) levels in patients enrolled in the placebo arms of IONIS-APO(a)<sub>Rx</sub> and IONIS-APO(a)-L<sub>Rx</sub> antisense oligonucleotide clinical trialsSantica M Marcovina, Nicholas J Viney, Steven G Hughes, et al.
European Heart Journal|July 23, 2019
N-acetyl galactosamine-conjugated antisense drug to APOC3 mRNA, triglycerides and atherogenic lipoprotein levelsVeronica J Alexander, Shuting Xia, Eunju Hurh, et al.
British Journal of Haematology|August 19, 2014
A randomized, open-label, multicentre, phase 2/3 study to evaluate the safety and efficacy of lumiliximab in combination with fludarabine, cyclophosphamide and rituximab versus fludarabine, cyclophosphamide and rituximab alone in subjects with relapsed chronic lymphocytic leukaemiaFarrukh T Awan, Peter Hillmen, Andrzej Hellmann, et al.
CNS Drugs|August 18, 2019
An Integrated Safety Analysis of Infants and Children with Symptomatic Spinal Muscular Atrophy (SMA) Treated with Nusinersen in Seven Clinical TrialsBasil T Darras, Michelle A Farrar, Eugenio Mercuri, et al.
Nucleic Acid Therapeutics|November 30, 2017
The Effects of 2'-O-Methoxyethyl Oligonucleotides on Renal Function in HumansStanley T Crooke, Brenda F Baker, Nguyen C Pham, et al.
Journal of the Neurological Sciences|September 17, 2018
Kind and distribution of cutaneous sensation loss in hereditary transthyretin amyloidosis with polyneuropathyMarcus V Pinto, P James B Dyck, Linde E Gove, et al.
Immunobiology|February 2, 2025
Inhibiting the alternative pathway of complement by reducing systemic complement factor B: Randomized, double-blind, placebo-controlled phase 1 studies with SefaxersenMichael L McCaleb, Steven G Hughes, Tamar R Grossman, et al.
Pageof 4

Showing results (1-10 of 32) with videos related to

Sort By:
Pageof 4
Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing|February 26, 2015
The effect of C-reactive protein reduction with a highly specific antisense oligonucleotide on atrial fibrillation assessed using beat-to-beat pacemaker Holter follow-upConn Sugihara, Nick Freemantle, Steven G Hughes, et al.
Arthritis Research & Therapy|April 18, 2015
Results of a proof of concept, double-blind, randomized trial of a second generation antisense oligonucleotide targeting high-sensitivity C-reactive protein (hs-CRP) in rheumatoid arthritisMarshelle S Warren, Steven G Hughes, Walter Singleton, et al.
Nucleic Acid Therapeutics|August 12, 2017
Lack of QT Prolongation for 2'-O-Methoxyethyl-Modified Antisense Oligonucleotides Based on Retrospective Exposure/Response Analysis of Ten Phase 1 Dose-Escalation Placebo-Controlled Studies in Healthy SubjectsRosie Z Yu, Rudy Gunawan, Richard S Geary, et al.
Journal of Clinical Lipidology|November 28, 2017
Temporal variability in lipoprotein(a) levels in patients enrolled in the placebo arms of IONIS-APO(a)<sub>Rx</sub> and IONIS-APO(a)-L<sub>Rx</sub> antisense oligonucleotide clinical trialsSantica M Marcovina, Nicholas J Viney, Steven G Hughes, et al.
European Heart Journal|July 23, 2019
N-acetyl galactosamine-conjugated antisense drug to APOC3 mRNA, triglycerides and atherogenic lipoprotein levelsVeronica J Alexander, Shuting Xia, Eunju Hurh, et al.
British Journal of Haematology|August 19, 2014
A randomized, open-label, multicentre, phase 2/3 study to evaluate the safety and efficacy of lumiliximab in combination with fludarabine, cyclophosphamide and rituximab versus fludarabine, cyclophosphamide and rituximab alone in subjects with relapsed chronic lymphocytic leukaemiaFarrukh T Awan, Peter Hillmen, Andrzej Hellmann, et al.
CNS Drugs|August 18, 2019
An Integrated Safety Analysis of Infants and Children with Symptomatic Spinal Muscular Atrophy (SMA) Treated with Nusinersen in Seven Clinical TrialsBasil T Darras, Michelle A Farrar, Eugenio Mercuri, et al.
Nucleic Acid Therapeutics|November 30, 2017
The Effects of 2'-O-Methoxyethyl Oligonucleotides on Renal Function in HumansStanley T Crooke, Brenda F Baker, Nguyen C Pham, et al.
Journal of the Neurological Sciences|September 17, 2018
Kind and distribution of cutaneous sensation loss in hereditary transthyretin amyloidosis with polyneuropathyMarcus V Pinto, P James B Dyck, Linde E Gove, et al.
Immunobiology|February 2, 2025
Inhibiting the alternative pathway of complement by reducing systemic complement factor B: Randomized, double-blind, placebo-controlled phase 1 studies with SefaxersenMichael L McCaleb, Steven G Hughes, Tamar R Grossman, et al.
Pageof 4