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Journal of Biomolecular Screening|August 12, 2006
Identification of small-molecule inhibitors of protein kinase B (PKB/AKT) in an AlphaScreenTM high-throughput screenSamantha Burns, Jonathan Travers, Ian Collins, et al.
Molecular Cancer Therapeutics|May 12, 2010
Mechanistic evaluation of the novel HSP90 inhibitor NVP-AUY922 in adult and pediatric glioblastomaNathalie Gaspar, Swee Y Sharp, Suzanne A Eccles, et al.
Blood|May 26, 2007
Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cellsEmma L Davenport, Hannah E Moore, Alan S Dunlop, et al.
Cancer Research|January 11, 2007
Role for amplification and expression of glypican-5 in rhabdomyosarcomaDaniel Williamson, Joanna Selfe, Tony Gordon, et al.
Plos One|April 24, 2012
The HSP90 inhibitor NVP-AUY922 radiosensitizes by abrogation of homologous recombination resulting in mitotic entry with unresolved DNA damageShane Zaidi, Martin McLaughlin, Shreerang A Bhide, et al.
Cell Cycle (Georgetown, Tex.)|January 30, 2009
Molecular pharmacology of phosphatidylinositol 3-kinase inhibition in human gliomaSandrine Guillard, Paul A Clarke, Robert Te Poele, et al.
Molecular Cancer Therapeutics|May 30, 2006
Potentiation of paclitaxel activity by the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin in human ovarian carcinoma cell lines with high levels of activated AKTNivedita Sain, Bhavani Krishnan, Michael G Ormerod, et al.
Plos One|July 10, 2020
Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancerSheelagh Frame, Chiara Saladino, Craig MacKay, et al.
The Biochemical Journal|August 15, 2019
Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP releaseCatarina Felisberto-Rodrigues, Jemima C Thomas, Craig McAndrew, et al.
Cancer Research|October 30, 2003
Molecular pharmacology of cancer therapy in human colorectal cancer by gene expression profilingPaul A Clarke, Mark L George, Sandra Easdale, et al.
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