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NAR Cancer|March 16, 2026
Human DEAH-box helicase 8 regulates HSF1-mediated stress response and cancer-associated pre-mRNA splicing in tumour cellsJennifer R Tall, Robert Te Poele, Alexandra Vasile, et al.
Molecular Cancer Therapeutics|April 29, 2010
AT7867 is a potent and oral inhibitor of AKT and p70 S6 kinase that induces pharmacodynamic changes and inhibits human tumor xenograft growthKyla M Grimshaw, Lisa-Jane K Hunter, Timothy A Yap, et al.
Journal of Medicinal Chemistry|December 15, 2017
Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766)Nicola E A Chessum, Swee Y Sharp, John J Caldwell, et al.
Nucleic Acids Research|November 13, 2024
canSAR 2024-an update to the public drug discovery knowledgebasePhillip W Gingrich, Rezvan Chitsazi, Ansuman Biswas, et al.
Bioorganic & Medicinal Chemistry|October 11, 2011
Design, synthesis and biological evaluation of 6-pyridylmethylaminopurines as CDK inhibitorsStuart C Wilson, Butrus Atrash, Clare Barlow, et al.
Journal of Medicinal Chemistry|November 8, 2013
Aurora isoform selectivity: design and synthesis of imidazo[4,5-b]pyridine derivatives as highly selective inhibitors of Aurora-A kinase in cellsVassilios Bavetsias, Amir Faisal, Simon Crumpler, et al.
Bioorganic & Medicinal Chemistry|October 27, 2005
Structure-based design of isoquinoline-5-sulfonamide inhibitors of protein kinase BIan Collins, John Caldwell, Tatiana Fonseca, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|February 3, 2018
HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic TargetJacqueline H L Fok, Somaieh Hedayat, Lei Zhang, et al.
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