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Aging Cell|September 13, 2022
Myeloid cell-specific mutation of Spi1 selectively reduces M2-biased macrophage numbers in skeletal muscle, reduces age-related muscle fibrosis and prevents sarcopeniaYing Wang, Steven S Welc, Michelle Wehling-Henricks, et al.
The American Journal of Pathology|January 15, 2025
Cytotoxic T-Lymphocyte-Associated Protein 4 Fused to a Modified Fragment of IgG1 Reduces Muscle Fiber Damage in a Model of Duchenne Muscular Dystrophy by Attenuating Proinflammatory Gene Expression in Myeloid Lineage CellsMichelle Wehling-Henricks, Su-Yin Kok, Haley Gamboa, et al.
Human Molecular Genetics|October 18, 2017
Macrophages escape Klotho gene silencing in the mdx mouse model of Duchenne muscular dystrophy and promote muscle growth and increase satellite cell numbers through a Klotho-mediated pathwayMichelle Wehling-Henricks, Steven S Welc, Guiseppina Samengo, et al.
Human Molecular Genetics|May 8, 2016
Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophyMichelle Wehling-Henricks, Zhenzhi Li, Catherine Lindsey, et al.
Cell Reports|June 27, 2024
Both enantiomers of β-aminoisobutyric acid BAIBA regulate Fgf23 via MRGPRD receptor by activating distinct signaling pathways in osteocytesEijiro Sakamoto, Yukiko Kitase, Alexander J Fitt, et al.
Human Molecular Genetics|November 1, 2016
Myeloid cells are capable of synthesizing aldosterone to exacerbate damage in muscular dystrophyJessica A Chadwick, Sarah A Swager, Jeovanna Lowe, et al.
The American Journal of Pathology|January 31, 2025
Klotho Is Cardioprotective in the mdx Mouse Model of Duchenne Muscular DystrophyAreli Jannes S Javier, Felicia M Kennedy, Xin Yi, et al.
Cell Death Discovery|March 1, 2026
BACH2 links β1-adrenergic receptor/β-arrestin1 signaling to MIAT to inhibit cardiac fibroblast activation and cardiomyocyte apoptosisBruno Moukette, Jian-Peng Teoh, Waleed J Hashmi, et al.
International Journal of Molecular Sciences|August 28, 2025
Klotho Deficiency Promotes Skeletal Muscle Weakness and Is Associated with Impaired Motor Unit ConnectivityLinda A Bean, Connor Thomas, Juan F Villa, et al.
Biorxiv : the Preprint Server for Biology|July 16, 2025
Klotho deficiency promotes skeletal muscle weakness and is associated with impaired motor unit connectivityLinda A Bean, Connor Thomas, Juan F Villa, et al.
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