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Biochemical Pharmacology|August 28, 2018
The deubiquitinase inhibitor b-AP15 induces strong proteotoxic stress and mitochondrial damageXiaonan Zhang, Paola Pellegrini, Amir Ata Saei, et al.Journal of Proteome Research|February 24, 2007
Large-scale proteomics analysis of human ovarian cancer for biomarkersSofia Bengtsson, Morten Krogh, Cristina Al-Khalili Szigyarto, et al.Frontiers in Oncology|May 9, 2022
Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mechanism of ActionJohannes Gubat, Karthik Selvaraju, Linda Sjöstrand, et al.Nature Medicine|November 8, 2011
Inhibition of proteasome deubiquitinating activity as a new cancer therapyPádraig D'Arcy, Slavica Brnjic, Maria Hägg Olofsson, et al.Molecular Pharmacology|April 10, 2014
The 19S Deubiquitinase inhibitor b-AP15 is enriched in cells and elicits rapid commitment to cell deathXin Wang, William Stafford, Magdalena Mazurkiewicz, et al.Plos One|December 8, 2017
Cytotoxicity of portoamides in human cancer cells and analysis of the molecular mechanisms of actionTiago Ribeiro, Filipa Lemos, Marco Preto, et al.Anticancer Research|April 1, 2009
Utilization of a right-handed coiled-coil protein from archaebacterium Staphylothermus marinus as a carrier for cisplatinMathilda Eriksson, Saadia Hassan, Rolf Larsson, et al.Biochemical Pharmacology|May 3, 2011
Phenotype-based drug screening in primary ovarian carcinoma cultures identifies intracellular iron depletion as a promising strategy for cancer treatmentJoachim Gullbo, Mårten Fryknäs, Linda Rickardson, et al.Cancer Cell International|September 29, 2018
A drug screening assay on cancer cells chronically adapted to acidosisPaola Pellegrini, Jason T Serviss, Thomas Lundbäck, et al.Blood|December 10, 2013
A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistanceZe Tian, Padraig D'Arcy, Xin Wang, et al.Pageof 13