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Blood|October 19, 2012
The high Nrf2 expression in human acute myeloid leukemia is driven by NF-κB and underlies its chemo-resistanceStuart A Rushworth, Lyubov Zaitseva, Megan Y Murray, et al.
Cellular Signalling|September 15, 2012
BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-κBStuart A Rushworth, Kristian M Bowles, Lawrence N Barrera, et al.
Molecules (Basel, Switzerland)|December 17, 2024
Increased Trypanocidal Activity of the Salinomycin Derivative Ironomycin Is Due to ROS Production and Iron Uptake ImpairmentDietmar Steverding, Stuart A Rushworth, Georgina R Hurle, et al.
Biochemical Society Transactions|August 12, 2014
Understanding life and death decisions in human leukaemiasDavid J MacEwan, Lawrence N Barrera, Sujitra Keadsanti, et al.
Scientific Reports|August 22, 2015
Targeting BTK for the treatment of FLT3-ITD mutated acute myeloid leukemiaGenevra Pillinger, Amina Abdul-Aziz, Lyubov Zaitseva, et al.
Experimental Parasitology|March 21, 2024
Suramin: Effectiveness of analogues reveals structural features that are important for the potent trypanocidal activity of the drugDietmar Steverding, Ryan A J Tinson, Monica Piras, et al.
Cell Cycle (Georgetown, Tex.)|January 8, 2015
Ibrutinib inhibits BTK-driven NF-κB p65 activity to overcome bortezomib-resistance in multiple myelomaMegan Y Murray, Lyubov Zaitseva, Martin J Auger, et al.
Oncotarget|October 9, 2014
Ibrutinib inhibits SDF1/CXCR4 mediated migration in AMLLyubov Zaitseva, Megan Y Murray, Manar S Shafat, et al.
Biomarker Research|May 14, 2021
Venetoclax and Daratumumab combination treatment demonstrates pre-clinical efficacy in mouse models of Acute Myeloid LeukemiaJayna J Mistry, Charlotte Hellmich, Amelia Lambert, et al.
Journal of Hematology & Oncology|May 18, 2018
Myeloma-derived macrophage inhibitory factor regulates bone marrow stromal cell-derived IL-6 via c-MYCRachel E Piddock, Christopher R Marlein, Amina Abdul-Aziz, et al.
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