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Plos One|August 25, 2020
An iron-dependent metabolic vulnerability underlies VPS34-dependence in RKO cancer cellsMarek J Kobylarz, Jonathan M Goodwin, Zhao B Kang, et al.Nature Cell Biology|October 21, 2014
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivoWilliam E Dowdle, Beat Nyfeler, Jane Nagel, et al.Nature Communications|May 16, 2022
Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathwayMona Hoseini Soflaee, Rushendhiran Kesavan, Umakant Sahu, et al.Nature Immunology|October 23, 2019
Fibroblastic reticular cells enhance T cell metabolism and survival via epigenetic remodelingFlavian D Brown, Debattama R Sen, Martin W LaFleur, et al.Cancer Discovery|December 7, 2011
Oncogenic EGFR signaling activates an mTORC2-NF-κB pathway that promotes chemotherapy resistanceKazuhiro Tanaka, Ivan Babic, David Nathanson, et al.Cell|March 24, 2018
Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H<sub>2</sub>S ProductionAlban Longchamp, Teodelinda Mirabella, Alessandro Arduini, et al.Cell Chemical Biology|July 10, 2025
A cereblon-based glue degrader of NEK7 regulates NLRP3 inflammasome in a context-dependent mannerAude Sylvain, Natacha Stoehr, Fupeng Ma, et al.JAMA Neurology|May 10, 2016
Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary MosaicismGhayda M Mirzaa, Catarina D Campbell, Nadia Solovieff, et al.Cancer Discovery|May 30, 2013
Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancerYan Liu, Kevin Marks, Glenn S Cowley, et al.Nature|June 29, 2017
mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancerAmaia Zabala-Letona, Amaia Arruabarrena-Aristorena, Natalia Martín-Martín, et al.Pageof 12