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Science (New York, N.Y.)|February 26, 2016
mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycleIssam Ben-Sahra, Gerta Hoxhaj, Stéphane J H Ricoult, et al.Molecular Cell|March 18, 2008
Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosisUmut Ozcan, Lale Ozcan, Erkan Yilmaz, et al.Genes & Development|July 20, 2005
Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2Brendan D Manning, M Nicole Logsdon, Alex I Lipovsky, et al.Proceedings of the National Academy of Sciences of the United States of America|September 25, 2002
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signalingAndrew R Tee, Diane C Fingar, Brendan D Manning, et al.Molecular and Cellular Biology|April 25, 2007
Mammalian DET1 regulates Cul4A activity and forms stable complexes with E2 ubiquitin-conjugating enzymesElah Pick, On-Sun Lau, Tomohiko Tsuge, et al.Current Biology : CB|April 23, 2002
The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1Xiaoming Yang, Suchithra Menon, Karin Lykke-Andersen, et al.Cancer Cell|July 21, 2004
The LKB1 tumor suppressor negatively regulates mTOR signalingReuben J Shaw, Nabeel Bardeesy, Brendan D Manning, et al.Nature Communications|November 28, 2013
The TSC-mTOR pathway regulates macrophage polarizationVanessa Byles, Anthony J Covarrubias, Issam Ben-Sahra, et al.Proceedings of the National Academy of Sciences of the United States of America|November 30, 2017
Improved detection of synthetic lethal interactions in <i>Drosophila</i> cells using variable dose analysis (VDA)Benjamin E Housden, Zhongchi Li, Colleen Kelley, et al.Plos One|July 14, 2009
Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathwayHui H Zhang, Jingxiang Huang, Katrin Düvel, et al.Pageof 12