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Cell Death Discovery|August 28, 2025
Discovery of Zharp1-163 as a dual inhibitor of ferroptosis and necroptosis for the treatment of inflammatory disorders and kidney injuryYuting Ji, Shujing Du, Jingjing Li, et al.
European Journal of Medicinal Chemistry|December 15, 2021
Design, synthesis, and evaluation of potent RIPK1 inhibitors with in vivo anti-inflammatory activityZhanhui Li, Yongjin Hao, Chengkui Yang, et al.
Nature Communications|March 28, 2015
Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteineTing Dong, Chao Li, Xing Wang, et al.
Apoptosis : an International Journal on Programmed Cell Death|May 18, 2020
Doxorubicin sensitizes cancer cells to Smac mimetic via synergistic activation of the CYLD/RIPK1/FADD/caspase-8-dependent apoptosisChengkui Yang, Qiao Ran, Yifei Zhou, et al.
Bioorganic Chemistry|September 17, 2022
Discovery, optimization and evaluation of isothiazolo[5,4-b]pyridine derivatives as RIPK1 inhibitors with potent in vivo anti-SIRS activityYongjin Hao, Chengkui Yang, Chang Shu, et al.
European Journal of Medicinal Chemistry|March 3, 2018
Discovery and characterization of a potent Wnt and hedgehog signaling pathways dual inhibitorHaikuo Ma, Qin Chen, Fang Zhu, et al.
Bioorganic & Medicinal Chemistry|October 13, 2015
Exploration of the linkage elements of porcupine antagonists led to potent Wnt signaling pathway inhibitorsYan Dong, Kehuang Li, Zhixiang Xu, et al.
The Journal of Cell Biology|January 20, 2016
Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversionKai Liu, Youli Jian, Xiaojuan Sun, et al.
Journal of Virology|November 13, 2015
Herpes Simplex Virus 1 (HSV-1) and HSV-2 Mediate Species-Specific Modulations of Programmed Necrosis through the Viral Ribonucleotide Reductase Large Subunit R1Xiaoliang Yu, Yun Li, Qin Chen, et al.
Biomaterials|September 18, 2016
Aqueous synthesized quantum dots interfere with the NF-κB pathway and confer anti-tumor, anti-viral and anti-inflammatory effectsZhilin Hu, Bin Song, Lei Xu, et al.
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