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The Journal of Biological Chemistry|July 3, 2021
STING-mediated degradation of IFI16 negatively regulates apoptosis by inhibiting p53 phosphorylation at serine 392Dapei Li, Lifen Xie, Zigang Qiao, et al.Bioorganic Chemistry|April 26, 2020
Design, synthesis, and evaluation of novel CXCR4 antagonists based on an aminoquinoline templateYu Lin, Zhanhui Li, Chen Xu, et al.European Journal of Medicinal Chemistry|August 10, 2020
Design, synthesis, and evaluation of pyrrolidine based CXCR4 antagonists with in vivo anti-tumor metastatic activityZhanhui Li, Xu Wang, Yu Lin, et al.Biochemical Pharmacology|June 14, 2023
Discovery of a novel RIPK2 inhibitor for the treatment of inflammatory bowel diseaseYujun Lai, Xinhui Wang, Xue Sun, et al.Journal of Medicinal Chemistry|December 20, 2016
Discovery of a Highly Potent, Selective, and Metabolically Stable Inhibitor of Receptor-Interacting Protein 1 (RIP1) for the Treatment of Systemic Inflammatory Response SyndromeYan Ren, Yaning Su, Liming Sun, et al.Cell Death Discovery|February 23, 2026
A viable kinase-inactive RIPK3 D143N mouse model reveals its scaffold function in driving TNF-induced inflammatory disorderYayun Du, Jingjing Li, Cong Zhao, et al.EMBO Reports|June 23, 2022
Interferon-mediated repression of miR-324-5p potentiates necroptosis to facilitate antiviral defenseXiaoyan Dou, Xiaoliang Yu, Shujing Du, et al.Chemmedchem|May 12, 2020
Design, Synthesis, and Characterization of Novel CXCR4 Antagonists Featuring Cyclic AminesYu Lin, Zhanhui Li, Haikuo Ma, et al.Proceedings of the National Academy of Sciences of the United States of America|March 1, 2017
Receptor-interacting protein kinase 3 promotes platelet activation and thrombosisYiwen Zhang, Jian Zhang, Rong Yan, et al.European Journal of Medicinal Chemistry|December 7, 2019
Structural optimization of aminopyrimidine-based CXCR4 antagonistsFang Zhu, Yujie Wang, Qian Du, et al.Pageof 6