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Frontiers in Cell and Developmental Biology|December 28, 2020
Discovery of a Potent RIPK3 Inhibitor for the Amelioration of Necroptosis-Associated Inflammatory InjuryKaijiang Xia, Fang Zhu, Chengkui Yang, et al.Cell Death & Disease|June 26, 2019
Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasisJue Hou, Jie Ju, Zili Zhang, et al.Hepatology (Baltimore, Md.)|September 20, 2024
Harnessing ZIKV NS2A RNA for alleviating acute hepatitis and cytokine release storm by targeting translation machineryJingfei Zhu, Rongsheng Wu, Tao Yang, et al.Leukemia|October 15, 2024
Anagrelide and idarubicin combination induces GSDME-mediated pyroptosis as a potential therapy for high-PDE3A acute myeloid leukemiaChenwei Yang, Yixin Hu, Li Gao, et al.The Journal of Cell Biology|October 31, 2023
Inhibition of lysosome-tethered Ragulator-Rag-3D complex restricts the replication of Enterovirus 71 and Coxsackie A16Xinhui Wang, Zhilin Hu, Wei Zhang, et al.Journal of Virology|August 16, 2022
XAF1 Protects Host against Emerging RNA Viruses by Stabilizing IRF1-Dependent Antiviral ImmunityYu Han, Xue Bai, Siying Liu, et al.Proceedings of the National Academy of Sciences of the United States of America|October 16, 2014
Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defenseXing Wang, Yun Li, Shan Liu, et al.American Journal of Human Genetics|July 5, 2011
Functional mutation of SMAC/DIABLO, encoding a mitochondrial proapoptotic protein, causes human progressive hearing loss DFNA64Jing Cheng, Yuhua Zhu, Sudan He, et al.Blood|November 10, 2022
A novel RIPK1 inhibitor reduces GVHD in mice via a nonimmunosuppressive mechanism that restores intestinal homeostasisXiaoliang Yu, Haikuo Ma, Bohan Li, et al.Cell Death and Differentiation|April 26, 2023
Apoptotic cell death in disease-Current understanding of the NCCD 2023Ilio Vitale, Federico Pietrocola, Emma Guilbaud, et al.Pageof 6