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The Journal of Pharmacology and Experimental Therapeutics|November 20, 2002
Differential regulation of expression of hepatic and pulmonary cytochrome P4501A enzymes by 3-methylcholanthrene in mice lacking the CYP1A2 geneSudha R Kondraganti, Weiwu Jiang, Bhagavatula Moorthy
Toxicological Sciences : an Official Journal of the Society of Toxicology|January 22, 2008
Persistent induction of hepatic and pulmonary phase II enzymes by 3-methylcholanthrene in ratsSudha R Kondraganti, Weiwu Jiang, Anil K Jaiswal, et al.
Chemical Research in Toxicology|November 23, 2005
Effects of 3-methylcholanthrene on gene expression profiling in the rat using cDNA microarray analysesSudha R Kondraganti, Kathirvel Muthiah, Weiwu Jiang, et al.
International Journal of Cancer|November 28, 2002
Polycyclic aromatic hydrocarbon-inducible DNA adducts: evidence by 32P-postlabeling and use of knockout mice for Ah receptor-independent mechanisms of metabolic activation in vivoSudha R Kondraganti, Pedro Fernandez-Salguero, Frank J Gonzalez, et al.
The Journal of Pharmacology and Experimental Therapeutics|March 22, 2003
Role of cytochrome P4501B1 in benzo[a]pyrene bioactivation to DNA-binding metabolites in mouse vascular smooth muscle cells: evidence from 32P-postlabeling for formation of 3-hydroxybenzo[a]pyrene and benzo[a]pyrene-3,6-quinone as major proximate genotoxic intermediatesBhagavatula Moorthy, Kimberly P Miller, Weiwu Jiang, et al.
Biochemical and Biophysical Research Communications|February 6, 2007
3-Methylcholanthrene elicits DNA adduct formation in the CYP1A1 promoter region and attenuates reporter gene expression in rat H4IIE cellsBhagavatula Moorthy, Kathirvel Muthiah, Inayat S Fazili, et al.
The Journal of Pharmacology and Experimental Therapeutics|August 25, 2010
Disruption of the gene for CYP1A2, which is expressed primarily in liver, leads to differential regulation of hepatic and pulmonary mouse CYP1A1 expression and augmented human CYP1A1 transcriptional activation in response to 3-methylcholanthrene in vivoWeiwu Jiang, Lihua Wang, Sudha R Kondraganti, et al.
The Journal of Pharmacology and Experimental Therapeutics|May 5, 2004
Disruption of the Ah receptor gene alters the susceptibility of mice to oxygen-mediated regulation of pulmonary and hepatic cytochromes P4501A expression and exacerbates hyperoxic lung injuryWeiwu Jiang, Stephen E Welty, Xanthi I Couroucli, et al.
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