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Journal of Medicinal Chemistry|March 6, 2023
Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis <i>In Vivo</i>John T Randolph, Matthew J O'Connor, Fei Han, et al.Journal of Medicinal Chemistry|June 5, 2025
Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library ScreenYunsong Tong, Kenton A Baker, Alex M Chapman, et al.Journal of Medicinal Chemistry|November 3, 2018
Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug DesignAdrian D Hobson, Russell A Judge, Ana L Aguirre, et al.Journal of Medicinal Chemistry|May 25, 2026
Discovery of Potent and Orally Bioavailable Novel Cluster of Differentiation 38 (CD38) Small Molecule InhibitorsReza Shiroodi, Timothy J Montavon, Brandon M Nelson, et al.Pageof 4