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Cells|October 13, 2023
An Overview of the Role of Furin in Type 2 DiabetesSulaiman K Marafie, Fahd Al-Mulla
International Journal of Molecular Sciences|June 19, 2024
mTOR: Its Critical Role in Metabolic Diseases, Cancer, and the Aging ProcessSulaiman K Marafie, Fahd Al-Mulla, Jehad Abubaker
Frontiers in Pharmacology|October 14, 2024
Notoginsenoside R1, a metabolite from Panax notoginseng (Burkill) F.H.Chen, stimulates insulin secretion through activation of phosphatidylinositol 3-kinase (PI3K)/Akt pathwayAltaf Al-Romaiyan, Ahmad Barakat, Sulaiman K Marafie, et al.
Biological Research|August 21, 2019
Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cellsSulaiman K Marafie, Eman M Al-Shawaf, Jehad Abubaker, et al.
Pharmaceuticals (Basel, Switzerland)|January 8, 2025
Targeting mTOR Kinase with Natural Compounds: Potent ATP-Competitive Inhibition Through Enhanced Binding MechanismsSulaiman K Marafie, Eman Alshawaf, Fahd Al-Mulla, et al.
Journal of Cellular and Molecular Medicine|May 24, 2025
Structural Modelling of Krüppel-Like Factor 15 Zinc Finger Binding Domain to DNA Using AlphaFold 3.0: Potential Therapeutic Target for Type 2 DiabetesAnwar Mohammad, Jehad Abubaker, Sulaiman K Marafie, et al.
International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases|October 19, 2020
Higher binding affinity of furin for SARS-CoV-2 spike (S) protein D614G mutant could be associated with higher SARS-CoV-2 infectivityAnwar Mohammad, Eman Alshawaf, Sulaiman K Marafie, et al.
Life Sciences|August 10, 2020
Structural analysis of ACE2 variant N720D demonstrates a higher binding affinity to TMPRSS2Anwar Mohammad, Sulaiman K Marafie, Eman Alshawaf, et al.
Biomolecules|April 30, 2021
Molecular Simulation-Based Investigation of Highly Potent Natural Products to Abrogate Formation of the nsp10-nsp16 Complex of SARS-CoV-2Anwar Mohammad, Eman Alshawaf, Sulaiman K Marafie, et al.
Microbial Pathogenesis|August 13, 2022
Discovery of natural products to block SARS-CoV-2 S-protein interaction with Neuropilin-1 receptor: A molecular dynamics simulation approachEman Alshawaf, Maha M Hammad, Sulaiman K Marafie, et al.
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