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Mbio|May 8, 2024
On-target, dual aminopeptidase inhibition provides cross-species antimalarial activityRebecca C S Edgar, Tess R Malcolm, Ghizal Siddiqui, et al.Neuron|July 11, 2008
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial AbetaPaul A Adlard, Robert A Cherny, David I Finkelstein, et al.Acta Neuropathologica Communications|June 30, 2017
The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's diseaseDavid I Finkelstein, Jessica L Billings, Paul A Adlard, et al.Journal of Medicinal Chemistry|November 30, 2021
Synthetic Sansanmycin Analogues as Potent <i>Mycobacterium tuberculosis</i> Translocase I InhibitorsWendy Tran, Ali S Kusay, Paige M E Hawkins, et al.Journal of Medicinal Chemistry|October 28, 2025
Optimization of Species-Selective Reversible Proteasome Inhibitors for the Treatment of MalariaSuraksha Gahalawat, Sneha Ray, Xiaoyu Zhang, et al.Frontiers in Chemistry|May 2, 2022
Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro InhibitorsDale J Calleja, Nathan Kuchel, Bernadine G C Lu, et al.Proceedings of the National Academy of Sciences of the United States of America|February 9, 2011
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malariaSusan A Charman, Sarah Arbe-Barnes, Ian C Bathurst, et al.Journal of Medicinal Chemistry|August 23, 2016
Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum TrypanosomacidesStephanie Russell, Raphaël Rahmani, Amy J Jones, et al.Journal of Medicinal Chemistry|June 24, 2011
Structure-guided lead optimization of triazolopyrimidine-ring substituents identifies potent Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidate potentialJose M Coteron, María Marco, Jorge Esquivias, et al.Journal of Medicinal Chemistry|April 30, 2016
Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial ActivitySreekanth Kokkonda, Xiaoyi Deng, Karen L White, et al.Pageof 18