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European Journal of Medicinal Chemistry|December 22, 2016
Novel inhibitors of Plasmodium falciparum based on 2,5-disubstituted furansSusann H Krake, Pablo David G Martinez, Jenna McLaren, et al.Journal of Medicinal Chemistry|May 8, 2014
Fluorine modulates species selectivity in the triazolopyrimidine class of Plasmodium falciparum dihydroorotate dehydrogenase inhibitorsXiaoyi Deng, Sreekanth Kokkonda, Farah El Mazouni, et al.Journal of Medicinal Chemistry|March 23, 2013
Discovery and structure-activity relationships of pyrrolone antimalarialsDinakaran Murugesan, Alka Mital, Marcel Kaiser, et al.ACS Infectious Diseases|February 16, 2023
<i>In Vitro</i> and <i>In Vivo</i> Antischistosomal Activity Profiling and Pharmacokinetics of Ozonide Carboxylic AcidsStefan Biendl, Cécile Häberli, Gong Chen, et al.Antimicrobial Agents and Chemotherapy|October 31, 2018
Inhibition of Cytomegalovirus Replication with Extended-Half-Life Synthetic OzonidesYiping Wang, Rupkatha Mukhopadhyay, Sujayita Roy, et al.Journal of Medicinal Chemistry|November 9, 2013
A prodrug approach toward cancer-related carbonic anhydrase inhibitionCindy J Carroux, Gregory M Rankin, Janina Moeker, et al.Bioorganic & Medicinal Chemistry Letters|December 19, 2012
Synthesis of acylated glycoconjugates as templates to investigate in vitro biopharmaceutical propertiesCindy J Carroux, Janina Moeker, Josephine Motte, et al.The Journal of Biological Chemistry|September 20, 2013
Complexes of Trypanosoma cruzi sterol 14α-demethylase (CYP51) with two pyridine-based drug candidates for Chagas disease: structural basis for pathogen selectivityTatiana Y Hargrove, Zdzislaw Wawrzak, Paul W Alexander, et al.Bioorganic & Medicinal Chemistry Letters|July 21, 2009
Spiroadamantyl 1,2,4-trioxolane, 1,2,4-trioxane, and 1,2,4-trioxepane pairs: relationship between peroxide bond iron(II) reactivity, heme alkylation efficiency, and antimalarial activityXiaofang Wang, Darren J Creek, Charles E Schiaffo, et al.British Journal of Clinical Pharmacology|July 5, 2012
First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarialsJoerg J Moehrle, Stephan Duparc, Christoph Siethoff, et al.Pageof 18