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The Journal of Pharmacology and Experimental Therapeutics|May 20, 2005
Dynamic activation of cystic fibrosis transmembrane conductance regulator by type 3 and type 4D phosphodiesterase inhibitorsSusana Liu, Alain Veilleux, Lei Zhang, et al.Journal of the Renin-Angiotensin-Aldosterone System : JRAAS|March 12, 2011
Characterization of a stable, hypertensive rat model suitable for the consecutive evaluation of human renin inhibitorsRené St-Jacques, Sylvie Toulmond, Anick Auger, et al.Bioorganic & Medicinal Chemistry Letters|March 7, 2006
Nitrogen-bridged substituted 8-arylquinolines as potent PDE IV inhibitorsPatrick Lacombe, Denis Deschênes, Daniel Dubé, et al.Bioorganic & Medicinal Chemistry Letters|July 31, 2009
Alkyl-bridged substituted 8-arylquinolines as highly potent PDE IV inhibitorsPatrick Lacombe, Nathalie Chauret, David Claveau, et al.Bioorganic & Medicinal Chemistry Letters|January 22, 2008
Design, synthesis, and biological evaluation of 8-biarylquinolines: a novel class of PDE4 inhibitorsMichel Gallant, Nathalie Chauret, David Claveau, et al.Bioorganic & Medicinal Chemistry Letters|October 12, 2010
Discovery of MK-0952, a selective PDE4 inhibitor for the treatment of long-term memory loss and mild cognitive impairmentMichel Gallant, Renee Aspiotis, Stephen Day, et al.Bioorganic & Medicinal Chemistry Letters|June 7, 2011
Renin inhibitors for the treatment of hypertension: design and optimization of a novel series of tertiary alcohol-bearing piperidinesAustin Chen, Elizabeth Cauchon, Amandine Chefson, et al.Bioorganic & Medicinal Chemistry Letters|May 31, 2011
Renin inhibitors for the treatment of hypertension: design and optimization of a novel series of pyridone-substituted piperidinesAustin Chen, Louis-Charles Campeau, Elizabeth Cauchon, et al.Frontiers in Immunology|June 6, 2025
Immunogenicity risk assessment for tailored mitigation and monitoring of biotherapeutics during development: recommendations from the European Immunogenicity PlatformJoanna Grudzinska-Goebel, Karin Benstein, Karien Bloem, et al.Bioorganic & Medicinal Chemistry Letters|September 20, 2005
Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: structure-activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitorDwight Macdonald, Anthony Mastracchio, Hélène Perrier, et al.Pageof 3