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Journal of Cellular and Molecular Medicine|July 19, 2011
Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic miceMikko Hiltunen, Vinoth K M Khandelwal, Nagendra Yaluri, et al.
The Journal of Nutritional Biochemistry|April 22, 2014
High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic statusMari Takalo, Annakaisa Haapasalo, Henna Martiskainen, et al.
Neurobiology of Aging|January 3, 2012
Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 miceSusanna Kemppainen, Tomi Rantamäki, André Jerónimo-Santos, et al.
Neurobiology of Aging|December 17, 2018
Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model miceSami Gabbouj, Teemu Natunen, Hennariikka Koivisto, et al.
Cell Reports|December 22, 2024
Physiological shedding and C-terminal proteolytic processing of TMEM106BSebastian Held, Christian Erck, Susanna Kemppainen, et al.
Molecular Neurodegeneration|November 10, 2020
Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaquesTeemu Natunen, Henna Martiskainen, Mikael Marttinen, et al.
Neurobiology of Disease|November 14, 2015
Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based modelsTeemu Natunen, Mari Takalo, Susanna Kemppainen, et al.
Neurobiology of Disease|April 29, 2023
Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture modelsRebekka Wittrahm, Mari Takalo, Teemu Kuulasmaa, et al.
Journal of Neuroinflammation|March 5, 2025
The protective PLCγ2-P522R variant mitigates Alzheimer's disease-associated pathologies by enhancing beneficial microglial functionsMari Takalo, Heli Jeskanen, Taisia Rolova, et al.
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