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Biochemical Pharmacology|July 17, 2026
Chimeric analysis links increased NO sensitivity to GC-2 domains and higher maximal activity to GC-1Svenja Stomberg, Sönke BehrendsEuropean Journal of Pharmacology|March 27, 2025
Discovery of the first isoform-specific sGC activator: Selective activation of GC-1 by runcaciguatSvenja Stomberg, Anne Rühle, Theresa Wittrien, et al.European Journal of Endocrinology|April 5, 2024
Heterozygous gain of function variant in GUCY1A2 may cause autonomous ovarian hyperfunctionTheresa Wittrien, Alban Ziegler, Anne Rühle, et al.Current Medicinal Chemistry|February 7, 2003
Drugs that activate specific nitric oxide sensitive guanylyl cyclase isoforms independent of nitric oxide releaseSönke BehrendsBiochemical Pharmacology|July 11, 2002
Biliverdin IX is an endogenous inhibitor of soluble guanylyl cyclaseMarkus Koglin, Sönke BehrendsThe Journal of Biological Chemistry|February 1, 2003
A functional domain of the alpha1 subunit of soluble guanylyl cyclase is necessary for activation of the enzyme by nitric oxide and YC-1 but is not involved in heme bindingMarkus Koglin, Sönke BehrendsBiochemical Pharmacology|March 26, 2004
Native human nitric oxide sensitive guanylyl cyclase: purification and characterizationMarkus Koglin, Sönke BehrendsBiochimica Et Biophysica Acta. Proteins and Proteomics|April 14, 2018
Synergistic stabilisation of NOsGC by cinaciguat and non-hydrolysable nucleotides: Evidence for sGC activator-induced communication between the heme-binding and catalytic domainsAnne Sömmer, Sönke BehrendsPlatelets|January 10, 2004
Analysis of nitric oxide-sensitive guanylyl cyclase in human platelets before and after aggregationJörg Kempfert, Sönke BehrendsNitric Oxide : Biology and Chemistry|April 30, 2018
Methods to investigate structure and activation dynamics of GC-1/GC-2Anne Sömmer, Sönke BehrendsPageof 4