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Nature|December 21, 2017
Structure of the mechanically activated ion channel Piezo1Kei Saotome, Swetha E Murthy, Jennifer M Kefauver, et al.
Biochemistry|April 20, 2012
The loss of an electrostatic contact unique to AMPA receptor ligand binding domain 2 slows channel activationSandra M Holley, Ahmed H Ahmed, Jayasri Srinivasan, et al.
Elife|November 2, 2018
Cryo-EM structure of the mechanically activated ion channel OSCA1.2Sebastian Jojoa-Cruz, Kei Saotome, Swetha E Murthy, et al.
Elife|November 2, 2018
OSCA/TMEM63 are an Evolutionarily Conserved Family of Mechanically Activated Ion ChannelsSwetha E Murthy, Adrienne E Dubin, Tess Whitwam, et al.
Nature Communications|February 15, 2022
Structural insights into the Venus flytrap mechanosensitive ion channel Flycatcher1Sebastian Jojoa-Cruz, Kei Saotome, Che Chun Alex Tsui, et al.
Cell|January 30, 2016
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic StrengthRuhma Syeda, Zhaozhu Qiu, Adrienne E Dubin, et al.
Science Translational Medicine|October 12, 2018
The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in miceSwetha E Murthy, Meaghan C Loud, Ihab Daou, et al.
Neuron|August 5, 2023
TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channelsWang Zheng, Shaun Rawson, Zhangfei Shen, et al.
Proceedings of the National Academy of Sciences of the United States of America|July 22, 2025
TMEM63A, associated with hypomyelinating leukodystrophies, is an evolutionarily conserved regulator of myelinationJulia Halford, Amanda J Senatore, Sage Berryman, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 25, 2014
Piezo1, a mechanically activated ion channel, is required for vascular development in miceSanjeev S Ranade, Zhaozhu Qiu, Seung-Hyun Woo, et al.
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