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Methods in Molecular Biology (Clifton, N.J.)|July 21, 2010
The use of human hepatocytes to investigate drug metabolism and CYP enzyme inductionSylvie Klieber, François Torreilles, François Guillou, et al.Biopharmaceutics & Drug Disposition|June 4, 2015
PBPK modeling of irbesartan: incorporation of hepatic uptakeHelene Chapy, Sylvie Klieber, Priscilla Brun, et al.Drug Metabolism Letters|October 15, 2014
Evaluation of human hepatocytes under prolonged culture in a novel medium for the maintenance of hepatic differentiation: results with the model pro-inflammatory cytokine interleukin 6Albert P Li, Qian Yang, Hélène Vermet, et al.Lab on a Chip|October 8, 2025
In situ formation and culture of cell spheroids in a low-binding 3D-printed biochipAlexandre Martins, Sylvie Klieber, Charlotte Le Graët, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 16, 2015
Evaluation of Normalization Methods To Predict CYP3A4 Induction in Six Fully Characterized Cryopreserved Human Hepatocyte Preparations and HepaRG CellsHélène Vermet, Nathalie Raoust, Robert Ngo, et al.CPT: Pharmacometrics & Systems Pharmacology|July 26, 2026
DDIapp-A Web-Based Application for Static Drug-Drug Interaction AssessmentHirotaka Watase, Sylvie Klieber, Yorgos M Psarellis, et al.Clinical Pharmacology and Therapeutics|November 15, 2023
Prediction of CYP Down Regulation after Tusamitamab Ravtansine Administration (a DM4-Conjugate), Based on an In Vitro-In Vivo Extrapolation ApproachClemence Pouzin, Donato Teutonico, Nathalie Fagniez, et al.Pharmacology Research & Perspectives|October 31, 2015
Applicability of second-generation upcyte® human hepatocytes for use in CYP inhibition and induction studiesSarada D Ramachandran, Aurélie Vivarès, Sylvie Klieber, et al.Journal of Pharmaceutical Sciences|March 11, 2018
Improving Prediction of Metabolic Clearance Using Quantitative Extrapolation of Results Obtained From Human Hepatic Micropatterned Cocultures Model and by Considering the Impact of Albumin BindingFranck Da-Silva, Xavier Boulenc, Hélène Vermet, et al.Journal of Labelled Compounds & Radiopharmaceuticals|November 29, 2013
Effect of deuteration on the metabolism and clearance of some pharmacologically active compounds--synthesis and in vitro metabolism of deuterated derivatives of dronedadroneJoseph Schofield, Denis Brasseur, Béatrice de Bruin, et al.Pageof 3