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T Abrams

Showing results (131-140 of 141) with videos related to

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Bioorganic & Medicinal Chemistry Letters|January 27, 2004
Macrocyclic piperazinones as potent dual inhibitors of farnesyltransferase and geranylgeranyltransferase-IChristopher J Dinsmore, C Blair Zartman, Jeffrey M Bergman, et al.
Bioorganic & Medicinal Chemistry Letters|March 31, 2007
Kinesin spindle protein (KSP) inhibitors. Part V: discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by beta-fluorination to overcome cellular efflux by P-glycoproteinChristopher D Cox, Michael J Breslin, David B Whitman, et al.
Blood Advances|June 25, 2020
Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malariaChristopher A Moxon, Yasir Alhamdi, Janet Storm, et al.
Bioorganic & Medicinal Chemistry Letters|September 29, 2007
Synthesis and evaluation of substituted benzoisoquinolinones as potent inhibitors of Chk1 kinaseRobert M Garbaccio, Shaei Huang, Edward S Tasber, et al.
International Journal of Pharmaceutics|March 11, 2014
An in vivo evaluation of amphiphilic, biodegradable peptide copolymers as siRNA delivery agentsStephanie E Barrett, Marc T Abrams, Rob Burke, et al.
Bioorganic & Medicinal Chemistry Letters|January 22, 2009
Development of thioquinazolinones, allosteric Chk1 kinase inhibitorsAntonella Converso, Timothy Hartingh, Robert M Garbaccio, et al.
Cancer Research|December 26, 2001
Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical modelsR B Lobell, C A Omer, M T Abrams, et al.
Bioorganic & Medicinal Chemistry Letters|July 19, 2001
Evaluation of amino acid-based linkers in potent macrocyclic inhibitors of farnesyl-protein transferaseD C Beshore, I M Bell, C J Dinsmore, et al.
Cancer Research|May 29, 2000
Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl:protein transferase inhibitorC A Omer, Z Chen, R E Diehl, et al.
Journal of Medicinal Chemistry|June 27, 2008
Kinesin spindle protein (KSP) inhibitors. 9. Discovery of (2S)-4-(2,5-difluorophenyl)-n-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the treatment of taxane-refractory cancerChristopher D Cox, Paul J Coleman, Michael J Breslin, et al.
Pageof 15

Showing results (131-140 of 141) with videos related to

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Pageof 15
Bioorganic & Medicinal Chemistry Letters|January 27, 2004
Macrocyclic piperazinones as potent dual inhibitors of farnesyltransferase and geranylgeranyltransferase-IChristopher J Dinsmore, C Blair Zartman, Jeffrey M Bergman, et al.
Bioorganic & Medicinal Chemistry Letters|March 31, 2007
Kinesin spindle protein (KSP) inhibitors. Part V: discovery of 2-propylamino-2,4-diaryl-2,5-dihydropyrroles as potent, water-soluble KSP inhibitors, and modulation of their basicity by beta-fluorination to overcome cellular efflux by P-glycoproteinChristopher D Cox, Michael J Breslin, David B Whitman, et al.
Blood Advances|June 25, 2020
Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malariaChristopher A Moxon, Yasir Alhamdi, Janet Storm, et al.
Bioorganic & Medicinal Chemistry Letters|September 29, 2007
Synthesis and evaluation of substituted benzoisoquinolinones as potent inhibitors of Chk1 kinaseRobert M Garbaccio, Shaei Huang, Edward S Tasber, et al.
International Journal of Pharmaceutics|March 11, 2014
An in vivo evaluation of amphiphilic, biodegradable peptide copolymers as siRNA delivery agentsStephanie E Barrett, Marc T Abrams, Rob Burke, et al.
Bioorganic & Medicinal Chemistry Letters|January 22, 2009
Development of thioquinazolinones, allosteric Chk1 kinase inhibitorsAntonella Converso, Timothy Hartingh, Robert M Garbaccio, et al.
Cancer Research|December 26, 2001
Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical modelsR B Lobell, C A Omer, M T Abrams, et al.
Bioorganic & Medicinal Chemistry Letters|July 19, 2001
Evaluation of amino acid-based linkers in potent macrocyclic inhibitors of farnesyl-protein transferaseD C Beshore, I M Bell, C J Dinsmore, et al.
Cancer Research|May 29, 2000
Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl:protein transferase inhibitorC A Omer, Z Chen, R E Diehl, et al.
Journal of Medicinal Chemistry|June 27, 2008
Kinesin spindle protein (KSP) inhibitors. 9. Discovery of (2S)-4-(2,5-difluorophenyl)-n-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the treatment of taxane-refractory cancerChristopher D Cox, Paul J Coleman, Michael J Breslin, et al.
Pageof 15