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Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 1, 2024
Candesartan Has No Clinically Meaningful Effect on the Plasma Concentrations of Cytochrome P450 2C8 Substrate Repaglinide in HumansMikael O W Piha, Kristiina Cajanus, Marica T Engström, et al.
Clinical Pharmacology and Therapeutics|June 2, 2022
Genomewide Association Study of Simvastatin PharmacokineticsAnssi J H Mykkänen, Suvi Taskinen, Mikko Neuvonen, et al.
The Journal of Pharmacology and Experimental Therapeutics|March 22, 2002
Dose optimization of a doxorubicin prodrug (HMR 1826) in isolated perfused human lungs: low tumor pH promotes prodrug activation by beta-glucuronidaseThomas E Mürdter, Godehard Friedel, Janne T Backman, et al.
Journal of Cachexia, Sarcopenia and Muscle|December 13, 2017
Prevention of chemotherapy-induced cachexia by ACVR2B ligand blocking has different effects on heart and skeletal muscleJuha J Hulmi, Tuuli A Nissinen, Markus Räsänen, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 2, 2016
VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protectionMarkus Räsänen, Joni Degerman, Tuuli A Nissinen, et al.
European Journal of Clinical Pharmacology|August 12, 2016
Voriconazole more likely than posaconazole increases plasma exposure to sublingual buprenorphine causing a risk of a clinically important interactionMari Fihlman, Tuija Hemmilä, Nora M Hagelberg, et al.
Clinical Pharmacology and Therapeutics|October 3, 2023
Ticagrelor Increases Exposure to the Breast Cancer Resistance Protein Substrate RosuvastatinMinna Lehtisalo, E Katriina Tarkiainen, Mikko Neuvonen, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|March 23, 2021
An automated cocktail method for in vitro assessment of direct and time-dependent inhibition of nine major cytochrome P450 enzymes - application to establishing CYP2C8 inhibitor selectivityHelinä Kahma, Laura Aurinsalo, Mikko Neuvonen, et al.
Human Reproduction (Oxford, England)|January 21, 2020
Anti-Müllerian hormone and letrozole levels in boys with constitutional delay of growth and puberty treated with letrozole or testosteroneE Kohva, T Varimo, H Huopio, et al.
Clinical Pharmacology and Therapeutics|March 3, 2025
Identification of Genetic Variants Associated with Pravastatin and Pitavastatin PharmacokineticsAnssi J H Mykkänen, E Katriina Tarkiainen, Suvi Taskinen, et al.
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