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ACS Medicinal Chemistry Letters|June 6, 2014
Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase InhibitorsMatthew T Burger, Mark Knapp, Allan Wagman, et al.Bioconjugate Chemistry|January 24, 2024
Design, Synthesis, and In Vitro and In Vivo Evaluation of Cereblon Binding Bruton's Tyrosine Kinase (BTK) Degrader CD79b Targeted Antibody-Drug ConjugatesAlan Zhang, Katherine Seiss, Laurent Laborde, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase InhibitorsMatthew T Burger, Wooseok Han, Jiong Lan, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating CancerMatthew T Burger, Sabina Pecchi, Allan Wagman, et al.Journal of Medicinal Chemistry|October 28, 2015
Identification of N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological MalignanciesMatthew T Burger, Gisele Nishiguchi, Wooseok Han, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|January 30, 2014
Pan-PIM kinase inhibition provides a novel therapy for treating hematologic cancersPablo D Garcia, John L Langowski, Yingyun Wang, et al.The CRISPR Journal|February 14, 2024
Generation of a Commercial-Scale Founder Population of Porcine Reproductive and Respiratory Syndrome Virus Resistant Pigs Using CRISPR-CasBrian T Burger, Benjamin P Beaton, Matthew A Campbell, et al.Journal of Medicinal Chemistry|May 31, 2017
Design and Discovery of N-(2-Methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant CancersGisele A Nishiguchi, Alice Rico, Huw Tanner, et al.Journal of Medicinal Chemistry|May 7, 2019
Design and Discovery of N-(3-(2-(2-Hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide, a Selective, Efficacious, and Well-Tolerated RAF Inhibitor Targeting RAS Mutant Cancers: The Path to the ClinicSavithri Ramurthy, Benjamin R Taft, Robert J Aversa, et al.Nature|December 8, 2022
Formation of robust bound states of interacting microwave photonsA Morvan, T I Andersen, X Mi, et al.Pageof 22