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Journal of Medicinal Chemistry|September 16, 1994
Rational design, synthesis, and crystallographic analysis of a hydroxyethylene-based HIV-1 protease inhibitor containing a heterocyclic P1'--P2' amide bond isostereS K Thompson, K H Murthy, B Zhao, et al.Proceedings of the National Academy of Sciences of the United States of America|March 1, 1989
Human immunodeficiency virus 1 protease expressed in Escherichia coli behaves as a dimeric aspartic proteaseT D Meek, B D Dayton, B W Metcalf, et al.Nature|January 14, 1990
Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analoguesT D Meek, D M Lambert, G B Dreyer, et al.Biochemical and Biophysical Research Communications|March 15, 1989
Peptide substrates and inhibitors of the HIV-1 proteaseM L Moore, W M Bryan, S A Fakhoury, et al.Antimicrobial Agents and Chemotherapy|May 11, 1992
Human immunodeficiency virus type 1 protease inhibitors irreversibly block infectivity of purified virions from chronically infected cellsD M Lambert, S R Petteway, C E McDanal, et al.Biochemistry|January 8, 2000
Mechanism of inhibition of cathepsin K by potent, selective 1, 5-diacylcarbohydrazides: a new class of mechanism-based inhibitors of thiol proteasesM J Bossard, T A Tomaszek, M A Levy, et al.Biochemistry|August 29, 2001
Steady-state kinetic characterization of substrates and metal-ion specificities of the full-length and N-terminally truncated recombinant human methionine aminopeptidases (type 2)G Yang, R B Kirkpatrick, T Ho, et al.Molecular and Cellular Neurosciences|November 24, 1999
Identification of a novel aspartic protease (Asp 2) as beta-secretaseI Hussain, D Powell, D R Howlett, et al.Molecular and Cellular Neurosciences|November 21, 2000
ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase siteI Hussain, D J Powell, D R Howlett, et al.Pageof 3