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Medchemcomm
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October 1, 2013
Diaryl- and triaryl-pyrrole derivatives: inhibitors of the MDM2-p53 and MDMX-p53 protein-protein interactions†Electronic supplementary information (ESI) available: Experimental details for compound synthesis, analytical data for all compounds and intermediates. Details for the biological evaluation. Further details for the modeling. Table of combustion analysis data. See DOI: 10.1039/c3md00161jClick here for additional data file
Tim J Blackburn, Shafiq Ahmed, Christopher R Coxon, et al.
Plos One
|
October 12, 2012
Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer
Kelly Coffey, Timothy J Blackburn, Susan Cook, et al.
Organic & Biomolecular Chemistry
|
February 23, 2018
Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach
Duncan C Miller, Mathew P Martin, Santosh Adhikari, et al.
Journal of Medicinal Chemistry
|
January 10, 2003
Tricyclic benzimidazoles as potent poly(ADP-ribose) polymerase-1 inhibitors
Donald J Skalitzky, Joseph T Marakovits, Karen A Maegley, et al.
Oncotarget
|
November 12, 2016
Structure-guided design of purine-based probes for selective Nek2 inhibition
Christopher R Coxon, Christopher Wong, Richard Bayliss, et al.
Journal of Medicinal Chemistry
|
December 6, 2013
8-Substituted O(6)-cyclohexylmethylguanine CDK2 inhibitors: using structure-based inhibitor design to optimize an alternative binding mode
Benoit Carbain, David J Paterson, Elizabeth Anscombe, et al.
RSC Medicinal Chemistry
|
January 22, 2021
2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase
Christopher J Matheson, Christopher R Coxon, Richard Bayliss, et al.
Journal of Medicinal Chemistry
|
July 17, 2013
1-substituted (Dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-ones endowed with dual DNA-PK/PI3-K inhibitory activity
Céline Cano, Kappusamy Saravanan, Chris Bailey, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 31, 2011
MDM2-p53 protein-protein interaction inhibitors: a-ring substituted isoindolinones
Anna F Watson, Junfeng Liu, Karim Bennaceur, et al.
Chemistry & Biology
|
September 1, 2015
Identification and Characterization of an Irreversible Inhibitor of CDK2
Elizabeth Anscombe, Elisa Meschini, Regina Mora-Vidal, et al.
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Search research articles
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Showing results (161-170 of 192) with videos related to
Sort By:
Page
of 20
Medchemcomm
|
October 1, 2013
Diaryl- and triaryl-pyrrole derivatives: inhibitors of the MDM2-p53 and MDMX-p53 protein-protein interactions†Electronic supplementary information (ESI) available: Experimental details for compound synthesis, analytical data for all compounds and intermediates. Details for the biological evaluation. Further details for the modeling. Table of combustion analysis data. See DOI: 10.1039/c3md00161jClick here for additional data file
Tim J Blackburn, Shafiq Ahmed, Christopher R Coxon, et al.
Plos One
|
October 12, 2012
Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer
Kelly Coffey, Timothy J Blackburn, Susan Cook, et al.
Organic & Biomolecular Chemistry
|
February 23, 2018
Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach
Duncan C Miller, Mathew P Martin, Santosh Adhikari, et al.
Journal of Medicinal Chemistry
|
January 10, 2003
Tricyclic benzimidazoles as potent poly(ADP-ribose) polymerase-1 inhibitors
Donald J Skalitzky, Joseph T Marakovits, Karen A Maegley, et al.
Oncotarget
|
November 12, 2016
Structure-guided design of purine-based probes for selective Nek2 inhibition
Christopher R Coxon, Christopher Wong, Richard Bayliss, et al.
Journal of Medicinal Chemistry
|
December 6, 2013
8-Substituted O(6)-cyclohexylmethylguanine CDK2 inhibitors: using structure-based inhibitor design to optimize an alternative binding mode
Benoit Carbain, David J Paterson, Elizabeth Anscombe, et al.
RSC Medicinal Chemistry
|
January 22, 2021
2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase
Christopher J Matheson, Christopher R Coxon, Richard Bayliss, et al.
Journal of Medicinal Chemistry
|
July 17, 2013
1-substituted (Dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-ones endowed with dual DNA-PK/PI3-K inhibitory activity
Céline Cano, Kappusamy Saravanan, Chris Bailey, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 31, 2011
MDM2-p53 protein-protein interaction inhibitors: a-ring substituted isoindolinones
Anna F Watson, Junfeng Liu, Karim Bennaceur, et al.
Chemistry & Biology
|
September 1, 2015
Identification and Characterization of an Irreversible Inhibitor of CDK2
Elizabeth Anscombe, Elisa Meschini, Regina Mora-Vidal, et al.
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