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Bioorganic & Medicinal Chemistry Letters
|
September 30, 2017
Identification of selective 8-(piperidin-4-yloxy)quinoline sulfone and sulfonamide histamine H<sub>1</sub> receptor antagonists for use in allergic rhinitis
Panayiotis A Procopiou, Alison J Ford, Paul M Gore, et al.
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
|
May 9, 2015
World Workshop on Oral Medicine VI: a systematic review of the treatment of mucous membrane pemphigoid
J Taylor, R McMillan, M Shephard, et al.
ACS Medicinal Chemistry Letters
|
May 20, 2017
Design of Phthalazinone Amide Histamine H<sub>1</sub> Receptor Antagonists for Use in Rhinitis
Panayiotis A Procopiou, Alison J Ford, Paul M Gore, et al.
Journal of Medicinal Chemistry
|
October 17, 2022
Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary Angioedema
Rebecca L Davie, Hannah J Edwards, D Michael Evans, et al.
Journal of Medicinal Chemistry
|
October 30, 2025
Correction to "Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary Angioedema"
Rebecca L Davie, Hannah J Edwards, D Michael Evans, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 13, 2011
Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor
Robert J Young, Wendy Alderton, Anthony D R Angell, et al.
Journal of Medicinal Chemistry
|
March 9, 2011
The discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitis
Panayiotis A Procopiou, Christopher Browning, Jennifer M Buckley, et al.
Journal of Medicinal Chemistry
|
December 7, 2007
4-acyl-1-(4-aminoalkoxyphenyl)-2-ketopiperazines as a novel class of non-brain-penetrant histamine H3 receptor antagonists
Panayiotis A Procopiou, Rachael A Ancliff, Mark J Bamford, et al.
Journal of Medicinal Chemistry
|
August 23, 2002
Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151)
Simon J F Macdonald, Michael D Dowle, Lee A Harrison, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 11, 2001
The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase--GW311616A a development candidate
S J Macdonald, M D Dowle, L A Harrison, et al.
Page
of 12
Search research articles
Search
Showing results (101-110 of 117) with videos related to
Sort By:
Page
of 12
Bioorganic & Medicinal Chemistry Letters
|
September 30, 2017
Identification of selective 8-(piperidin-4-yloxy)quinoline sulfone and sulfonamide histamine H<sub>1</sub> receptor antagonists for use in allergic rhinitis
Panayiotis A Procopiou, Alison J Ford, Paul M Gore, et al.
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
|
May 9, 2015
World Workshop on Oral Medicine VI: a systematic review of the treatment of mucous membrane pemphigoid
J Taylor, R McMillan, M Shephard, et al.
ACS Medicinal Chemistry Letters
|
May 20, 2017
Design of Phthalazinone Amide Histamine H<sub>1</sub> Receptor Antagonists for Use in Rhinitis
Panayiotis A Procopiou, Alison J Ford, Paul M Gore, et al.
Journal of Medicinal Chemistry
|
October 17, 2022
Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary Angioedema
Rebecca L Davie, Hannah J Edwards, D Michael Evans, et al.
Journal of Medicinal Chemistry
|
October 30, 2025
Correction to "Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary Angioedema"
Rebecca L Davie, Hannah J Edwards, D Michael Evans, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 13, 2011
Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor
Robert J Young, Wendy Alderton, Anthony D R Angell, et al.
Journal of Medicinal Chemistry
|
March 9, 2011
The discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitis
Panayiotis A Procopiou, Christopher Browning, Jennifer M Buckley, et al.
Journal of Medicinal Chemistry
|
December 7, 2007
4-acyl-1-(4-aminoalkoxyphenyl)-2-ketopiperazines as a novel class of non-brain-penetrant histamine H3 receptor antagonists
Panayiotis A Procopiou, Rachael A Ancliff, Mark J Bamford, et al.
Journal of Medicinal Chemistry
|
August 23, 2002
Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151)
Simon J F Macdonald, Michael D Dowle, Lee A Harrison, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 11, 2001
The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase--GW311616A a development candidate
S J Macdonald, M D Dowle, L A Harrison, et al.
Page
of 12