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Bioorganic & Medicinal Chemistry
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July 27, 2021
Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of novel reversible Bruton's tyrosine kinase inhibitors
Brian T Hopkins, Eris Bame, Noah Bell, et al.
Journal of Medicinal Chemistry
|
April 7, 2026
Leveraging Kinase Drugs for Neurosciences: Discovery of Selective, CNS-Penetrant Reversible Bruton's Tyrosine Kinase Inhibitors as Therapeutics for Neuroinflammation
Brian T Hopkins, Isaac E Marx, Harlod George Vandeveer, et al.
Clinical & Translational Immunology
|
June 18, 2021
Next-generation Bruton's tyrosine kinase inhibitor BIIB091 selectively and potently inhibits B cell and Fc receptor signaling and downstream functions in B cells and myeloid cells
Eris Bame, Hao Tang, Jeremy C Burns, et al.
Journal of Medicinal Chemistry
|
November 4, 2021
Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis
Brian T Hopkins, Eris Bame, Bekim Bajrami, et al.
Journal of Medicinal Chemistry
|
May 7, 2024
Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis
Martin K Himmelbauer, Bekim Bajrami, Rebecca Basile, et al.
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Search research articles
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Showing results (91-100 of 95) with videos related to
Sort By:
Page
of 10
You have reached the last page of results.
This site can display upto 95 results.
Bioorganic & Medicinal Chemistry
|
July 27, 2021
Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of novel reversible Bruton's tyrosine kinase inhibitors
Brian T Hopkins, Eris Bame, Noah Bell, et al.
Journal of Medicinal Chemistry
|
April 7, 2026
Leveraging Kinase Drugs for Neurosciences: Discovery of Selective, CNS-Penetrant Reversible Bruton's Tyrosine Kinase Inhibitors as Therapeutics for Neuroinflammation
Brian T Hopkins, Isaac E Marx, Harlod George Vandeveer, et al.
Clinical & Translational Immunology
|
June 18, 2021
Next-generation Bruton's tyrosine kinase inhibitor BIIB091 selectively and potently inhibits B cell and Fc receptor signaling and downstream functions in B cells and myeloid cells
Eris Bame, Hao Tang, Jeremy C Burns, et al.
Journal of Medicinal Chemistry
|
November 4, 2021
Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis
Brian T Hopkins, Eris Bame, Bekim Bajrami, et al.
Journal of Medicinal Chemistry
|
May 7, 2024
Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis
Martin K Himmelbauer, Bekim Bajrami, Rebecca Basile, et al.
Page
of 10