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Molecular Cancer Therapeutics|September 20, 2005
The phosphatidylinositol-3-kinase inhibitor PX-866 overcomes resistance to the epidermal growth factor receptor inhibitor gefitinib in A-549 human non-small cell lung cancer xenograftsNathan T Ihle, Gillian Paine-Murrieta, Margareta I Berggren, et al.Molecular Cancer Therapeutics|July 15, 2004
Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signalingNathan T Ihle, Ryan Williams, Sherry Chow, et al.Molecular Cancer Therapeutics|May 15, 2023
Efficacy and Imaging-Enabled Pharmacodynamic Profiling of KRAS G12C Inhibitors in Xenograft and Genetically Engineered Mouse Models of CancerCatherine Lee, Ziyue Karen Jiang, Simon Planken, et al.Cancer Research|May 2, 2019
An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and TumorsMartin Indarte, Roisin Puentes, Marco Maruggi, et al.Cell|October 3, 2017
Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined CancerLiron Bar-Peled, Esther K Kemper, Radu M Suciu, et al.Journal of the National Cancer Institute|January 17, 2012
Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcomeNathan T Ihle, Lauren A Byers, Edward S Kim, et al.Pageof 3