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Nucleosides, Nucleotides & Nucleic Acids|May 10, 2017
Comparison of DNA fragments as donor DNAs upon sequence conversion of cleaved target DNATetsuya Suzuki, Takashi Imada, Yasuo Komatsu, et al.Genes to Cells : Devoted to Molecular & Cellular Mechanisms|February 20, 2021
RNA polymerase II condensate formation and association with Cajal and histone locus bodies in living human cellsTakashi Imada, Takeshi Shimi, Ai Kaiho, et al.Biological & Pharmaceutical Bulletin|August 2, 2016
Cleavage of Target DNA Promotes Sequence Conversion with a Tailed DuplexTetsuya Suzuki, Takashi Imada, Natsuki Nishigaki, et al.Journal of Medicinal Chemistry|June 23, 2006
Design, synthesis, and structure-activity relationships of thieno[2,3-b]pyridin-4-one derivatives as a novel class of potent, orally active, non-peptide luteinizing hormone-releasing hormone receptor antagonistsTakashi Imada, Nobuo Cho, Toshihiro Imaeda, et al.Bioorganic & Medicinal Chemistry|July 3, 2013
Synthetic studies of centromere-associated protein-E (CENP-E) inhibitors: 1.Exploration of fused bicyclic core scaffolds using electrostatic potential mapTakaharu Hirayama, Masanori Okaniwa, Takashi Imada, et al.Journal of Medicinal Chemistry|June 11, 2011
Discovery of 1-{4-[1-(2,6-difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl}-3-methoxyurea (TAK-385) as a potent, orally active, non-peptide antagonist of the human gonadotropin-releasing hormone receptorKazuhiro Miwa, Takenori Hitaka, Takashi Imada, et al.ACS Synthetic Biology|October 3, 2018
A Highly Bioactive Lys-Deficient IFN Leads to a Site-Specific Di-PEGylated IFN with Equivalent Bioactivity to That of Unmodified IFN-α2bTakashi Imada, Koji Moriya, Masahiko Uchiyama, et al.Bioorganic & Medicinal Chemistry|July 6, 2012
Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 2. Synthesis and characterization of a novel imide-type prodrug for improving oral absorptionMasanori Okaniwa, Takashi Imada, Tomohiro Ohashi, et al.Bioorganic & Medicinal Chemistry Letters|April 2, 2017
Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivativesMoriteru Asano, Takenori Hitaka, Takashi Imada, et al.Journal of Medicinal Chemistry|January 3, 2020
Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-<i>d</i>]pyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active Investigational Antitumor AgentOsamu Kurasawa, Tohru Miyazaki, Misaki Homma, et al.Pageof 2