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Bioorganic & Medicinal Chemistry|August 14, 2012
Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivativesMasaaki Hirose, Masanori Okaniwa, Tohru Miyazaki, et al.Journal of Medicinal Chemistry|March 2, 2012
Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors. 1. Exploration of [5,6]-fused bicyclic scaffoldsMasanori Okaniwa, Masaaki Hirose, Takashi Imada, et al.Journal of Medicinal Chemistry|January 18, 2019
Design, Synthesis, and Biological Evaluation of Retinoic Acid-Related Orphan Receptor γt (RORγt) Agonist Structure-Based Functionality Switching Approach from In House RORγt Inverse Agonist to RORγt AgonistTomoya Yukawa, Yoshi Nara, Mitsunori Kono, et al.Bioorganic & Medicinal Chemistry|December 21, 2017
Discovery of orally efficacious RORγt inverse agonists. Part 2: Design, synthesis, and biological evaluation of novel tetrahydroisoquinoline derivativesMitsunori Kono, Tsuneo Oda, Michiko Tawada, et al.Science Advances|May 28, 2019
Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitorKenichi Iwai, Tadahiro Nambu, Ryo Dairiki, et al.Journal of Medicinal Chemistry|March 7, 2018
Discovery of [ cis-3-({(5 R)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1 H-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5 H)-yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse AgonistMitsunori Kono, Atsuko Ochida, Tsuneo Oda, et al.Pageof 2