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Bioorganic & Medicinal Chemistry|June 10, 2006
Synthesis, SAR studies, and pharmacological evaluation of 3-anilino-4-(3-indolyl) maleimides with conformationally restricted structure as orally bioavailable PKCbeta-selective inhibitorsMasahiro Tanaka, Shoichi Sagawa, Jun-ichi Hoshi, et al.European Journal of Medicinal Chemistry|September 25, 2018
Discovery of potent liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitors, thiazole-4-acetic acid derivatives, for the treatment of diabetes, hepatic steatosis, and obesityTetsuya Iida, Minoru Ubukata, Ikuo Mitani, et al.Bioorganic & Medicinal Chemistry Letters|February 27, 2009
Novel N-substituted 2-phenyl-1-sulfonylamino-cyclopropane carboxylates as selective ADAMTS-5 (Aggrecanase-2) inhibitorsMakoto Shiozaki, Katsuya Maeda, Tomoya Miura, et al.Bioorganic & Medicinal Chemistry Letters|September 22, 2009
Synthesis and SAR of 2-phenyl-1-sulfonylaminocyclopropane carboxylates as ADAMTS-5 (Aggrecanase-2) inhibitorsMakoto Shiozaki, Hiroto Imai, Katsuya Maeda, et al.Journal of Medicinal Chemistry|March 23, 2011
Discovery of (1S,2R,3R)-2,3-dimethyl-2-phenyl-1-sulfamidocyclopropanecarboxylates: novel and highly selective aggrecanase inhibitorsMakoto Shiozaki, Katsuya Maeda, Tomoya Miura, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of a Highly Potent and Selective MEK Inhibitor: GSK1120212 (JTP-74057 DMSO Solvate)Hiroyuki Abe, Shinichi Kikuchi, Kazuhide Hayakawa, et al.Journal of Medicinal Chemistry|March 28, 2014
Discovery of 6-phenylpyrimido[4,5-b][1,4]oxazines as potent and selective acyl CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitors with in vivo efficacy in rodentsBrian M Fox, Kazuyuki Sugimoto, Kiyosei Iio, et al.Pageof 3