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Journal of Pharmaceutical Sciences
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July 23, 2009
Kinetic assessment of luminal degradation of orally effective prodrugs for rational drug development
Takashi Mizuma
Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica
|
September 15, 2009
Impact of intestinal metabolism on drug development
Takashi Mizuma
Drug Metabolism and Pharmacokinetics
|
December 25, 2004
Kinetic impact of presystemic intestinal metabolism on drug absorption: experiment and data analysis for the prediction of in vivo absorption from in vitro data
Takashi Mizuma
International Journal of Pharmaceutics
|
June 3, 2009
Intestinal glucuronidation metabolism may have a greater impact on oral bioavailability than hepatic glucuronidation metabolism in humans: a study with raloxifene, substrate for UGT1A1, 1A8, 1A9, and 1A10
Takashi Mizuma
Journal of Pharmaceutical Sciences
|
April 3, 2008
Assessment of presystemic and systemic intestinal availability of orally administered drugs using in vitro and in vivo data in humans: intestinal sulfation metabolism impacts presystemic availability much more than systemic availability of salbutamol, SULT1A3 substrate
Takashi Mizuma
Journal of Pharmaceutical Sciences
|
August 6, 2004
Dietary polyphenols (-)-epicatechin and chrysin inhibit intestinal glucuronidation metabolism to increase drug absorption
Takashi Mizuma, Shoji Awazu
Biological Procedures Online
|
May 8, 2003
The Metabolic Inhibition Model Which Predicts the Intestinal Absorbability and Metabolizability of Drug: Theory and Experiment
Takashi Mizuma, Shoji Awazu
The Journal of Pharmacy and Pharmacology
|
May 20, 2005
Kinetic characterization of glycosidase activity from disaccharide conjugate to monosaccharide conjugate in Caco-2 cells
Takashi Mizuma, Norihiko Fuseda, Masahiro Hayashi
Biological & Pharmaceutical Bulletin
|
November 6, 2003
Concentration-dependent atypical intestinal absorption of cyclic phenylalanylserine: small intestine acts as an interface between the body and ingested compounds
Takashi Mizuma, Takuo Narasaka, Shoji Awazu
The Journal of Pharmacy and Pharmacology
|
October 3, 2002
Uptake of cyclic dipeptide by PEPT1 in Caco-2 cells: phenolic hydroxyl group of substrate enhances affinity for PEPT1
Takashi Mizuma, Takuo Narasaka, Shoji Awazu
Page
of 2
Search research articles
Search
Showing results (1-10 of 17) with videos related to
Sort By:
Page
of 2
Journal of Pharmaceutical Sciences
|
July 23, 2009
Kinetic assessment of luminal degradation of orally effective prodrugs for rational drug development
Takashi Mizuma
Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica
|
September 15, 2009
Impact of intestinal metabolism on drug development
Takashi Mizuma
Drug Metabolism and Pharmacokinetics
|
December 25, 2004
Kinetic impact of presystemic intestinal metabolism on drug absorption: experiment and data analysis for the prediction of in vivo absorption from in vitro data
Takashi Mizuma
International Journal of Pharmaceutics
|
June 3, 2009
Intestinal glucuronidation metabolism may have a greater impact on oral bioavailability than hepatic glucuronidation metabolism in humans: a study with raloxifene, substrate for UGT1A1, 1A8, 1A9, and 1A10
Takashi Mizuma
Journal of Pharmaceutical Sciences
|
April 3, 2008
Assessment of presystemic and systemic intestinal availability of orally administered drugs using in vitro and in vivo data in humans: intestinal sulfation metabolism impacts presystemic availability much more than systemic availability of salbutamol, SULT1A3 substrate
Takashi Mizuma
Journal of Pharmaceutical Sciences
|
August 6, 2004
Dietary polyphenols (-)-epicatechin and chrysin inhibit intestinal glucuronidation metabolism to increase drug absorption
Takashi Mizuma, Shoji Awazu
Biological Procedures Online
|
May 8, 2003
The Metabolic Inhibition Model Which Predicts the Intestinal Absorbability and Metabolizability of Drug: Theory and Experiment
Takashi Mizuma, Shoji Awazu
The Journal of Pharmacy and Pharmacology
|
May 20, 2005
Kinetic characterization of glycosidase activity from disaccharide conjugate to monosaccharide conjugate in Caco-2 cells
Takashi Mizuma, Norihiko Fuseda, Masahiro Hayashi
Biological & Pharmaceutical Bulletin
|
November 6, 2003
Concentration-dependent atypical intestinal absorption of cyclic phenylalanylserine: small intestine acts as an interface between the body and ingested compounds
Takashi Mizuma, Takuo Narasaka, Shoji Awazu
The Journal of Pharmacy and Pharmacology
|
October 3, 2002
Uptake of cyclic dipeptide by PEPT1 in Caco-2 cells: phenolic hydroxyl group of substrate enhances affinity for PEPT1
Takashi Mizuma, Takuo Narasaka, Shoji Awazu
Page
of 2