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Expert Opinion on Therapeutic Patents|September 22, 2023
CDC7 kinase inhibitors: a survey of recent patent literature (2017-2022)Takayuki Irie, Masaaki SawaChemical & Pharmaceutical Bulletin|January 10, 2018
7-Azaindole: A Versatile Scaffold for Developing Kinase InhibitorsTakayuki Irie, Masaaki SawaBioorganic & Medicinal Chemistry Letters|November 23, 2011
Design and combinatorial synthesis of a novel kinase-focused library using click chemistry-based fragment assemblyTakayuki Irie, Ikuo Fujii, Masaaki SawaBioorganic & Medicinal Chemistry Letters|December 5, 2017
Design and synthesis of novel pyrimidine analogs as highly selective, non-covalent BTK inhibitorsWataru Kawahata, Tokiko Asami, Takayuki Irie, et al.The Journal of Organic Chemistry|April 24, 2008
Application of 2-pyridyl-substituted hemithioindigo as a molecular switch in hydrogen-bonded porphyrinsKiyoshi Tanaka, Kiyoshi Kohayakawa, Satoru Iwata, et al.Bioscience, Biotechnology, and Biochemistry|September 13, 2002
Recognition of a cysteine substrate by E. coli gamma-glutamylcysteine synthetase probed by sulfoximine-based transition-state analogue inhibitorsJun Hiratake, Takayuki Irie, Nobuya Tokutake, et al.Journal of Medicinal Chemistry|September 16, 2021
Discovery of AS-1763: A Potent, Selective, Noncovalent, and Orally Available Inhibitor of Bruton's Tyrosine KinaseWataru Kawahata, Tokiko Asami, Takao Kiyoi, et al.Journal of Medicinal Chemistry|October 5, 2021
Discovery of AS-0141, a Potent and Selective Inhibitor of CDC7 Kinase for the Treatment of Solid CancersTakayuki Irie, Tokiko Asami, Ayako Sawa, et al.Journal of Medicinal Chemistry|September 15, 2018
Design and Synthesis of Novel Amino-triazine Analogues as Selective Bruton's Tyrosine Kinase Inhibitors for Treatment of Rheumatoid ArthritisWataru Kawahata, Tokiko Asami, Takao Kiyoi, et al.European Journal of Medicinal Chemistry|March 11, 2017
Discovery of novel furanone derivatives as potent Cdc7 kinase inhibitorsTakayuki Irie, Tokiko Asami, Ayako Sawa, et al.Pageof 1