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Journal of Medicinal Chemistry|February 3, 2006
Identification of a novel spiropiperidine opioid receptor-like 1 antagonist class by a focused library approach featuring 3D-pharmacophore similarityYasuhiro Goto, Sachie Arai-Otsuki, Yukari Tachibana, et al.Journal of Glaucoma|November 19, 2013
Safety and Efficacy of Benzalkonium Chloride-optimized Tafluprost in Japanese Glaucoma Patients With Existing Superficial Punctate KeratitisKatsuyoshi Suzuki, Shinichiro Teranishi, Takeshi Sagara, et al.Cancer Research|September 25, 2020
Futibatinib Is a Novel Irreversible FGFR 1-4 Inhibitor That Shows Selective Antitumor Activity against FGFR-Deregulated TumorsHiroshi Sootome, Hidenori Fujita, Kenjiro Ito, et al.Journal of Medicinal Chemistry|June 23, 2009
Identification of an orally active opioid receptor-like 1 (ORL1) receptor antagonist 4-{3-[(2R)-2,3-dihydroxypropyl]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl}-1-[(1S,3S,4R)-spiro[bicyclo[2.2.1]heptane-2,1'-cyclopropan]-3-ylmethyl]piperidine as clinical candidateAtsushi Satoh, Takeshi Sagara, Hiroki Sakoh, et al.ACS Medicinal Chemistry Letters|April 20, 2023
Discovery of Futibatinib: The First Covalent FGFR Kinase Inhibitor in Clinical UseSatoru Ito, Sachie Otsuki, Hirokazu Ohsawa, et al.Cell Death Discovery|July 2, 2024
The anti-tumor effect of trifluridine via induction of aberrant mitosis is unaffected by mutations modulating p53 activityTakeshi Wakasa, Kentaro Nonaka, Akihito Harada, et al.Molecular Cancer Therapeutics|November 6, 2009
Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agentsHiroshi Hirai, Yoshikazu Iwasawa, Megumu Okada, et al.Investigative Ophthalmology & Visual Science|July 1, 2008
Association of Toll-like receptor 4 gene polymorphisms with normal tension glaucomaEtsuko Shibuya, Akira Meguro, Masao Ota, et al.Clinical Ophthalmology (Auckland, N.Z.)|August 12, 2009
Association of microsatellite polymorphisms of the GPDS1 locus with normal tension glaucoma in the Japanese populationKayo Nakamura, Masao Ota, Akira Meguro, et al.Molecular Vision|April 30, 2011
Investigation of the association between SLC1A3 gene polymorphisms and normal tension glaucomaReiko Yasumura, Akira Meguro, Masao Ota, et al.Pageof 4