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Chemical & Pharmaceutical Bulletin|January 7, 2020
Discovery of 3,5-Dimethylpyridin-4(1H)-one Derivatives as Activators of AMP-Activated Protein Kinase (AMPK)Kazuyuki Kuramoto, Yuki Sawada, Naoki Ishibashi, et al.
European Journal of Pharmacology|July 27, 2010
Effects of the novel Foxo1 inhibitor AS1708727 on plasma glucose and triglyceride levels in diabetic db/db miceHirotsugu Tanaka, Takeyuki Nagashima, Akiyoshi Shimaya, et al.
Chemical & Pharmaceutical Bulletin|May 8, 2020
Novel Indirect AMP-Activated Protein Kinase Activators: Identification of a Second-Generation Clinical Candidate with Improved Physicochemical Properties and Reduced hERG Inhibitory ActivityKazuyuki Kuramoto, Yuki Sawada, Tomohiro Yamada, et al.
Bioorganic & Medicinal Chemistry Letters|March 12, 2004
Mass-tag technology for monitoring of protein kinase activity using mass spectrometryTatsuhiko Sonoda, Syuhei Shigaki, Takeyuki Nagashima, et al.
Bioorganic & Medicinal Chemistry|February 3, 2020
Development of a potent and orally active activator of adenosine monophosphate-activated protein kinase (AMPK), ASP4132, as a clinical candidate for the treatment of human cancerKazuyuki Kuramoto, Hiroyoshi Yamada, Takashi Shin, et al.
Molecular Pharmacology|August 26, 2010
Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db miceTakeyuki Nagashima, Nobuharu Shigematsu, Riyo Maruki, et al.
Biochemical Pharmacology|April 29, 2005
Protective effect of FK506 against apoptosis of SH-SY5Y cells correlates with regulation of the serum inducible kinase geneMasakazu Muramoto, Takao Yamazaki, Noriyuki Morikawa, et al.
British Journal of Cancer|November 19, 2021
Characterisation of a novel KRAS G12C inhibitor ASP2453 that shows potent anti-tumour activity in KRAS G12C-mutated preclinical modelsAyako Nakayama, Takeyuki Nagashima, Yoshihiro Nishizono, et al.
American Journal of Primatology|September 11, 2003
Collection and analysis of hematopoietic progenitor cells from cynomolgus macaques (Macaca fascicularis): assessment of cross-reacting monoclonal antibodiesHiroaki Shibata, Yutaka Hanazono, Naohide Ageyama, et al.
Neuropharmacology|January 4, 2006
Diclofenac, a non-steroidal anti-inflammatory drug, suppresses apoptosis induced by endoplasmic reticulum stresses by inhibiting caspase signalingTakao Yamazaki, Masakazu Muramoto, Tomoya Oe, et al.
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