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Clinical and Translational Allergy|June 23, 2021
Long-term safety and effectiveness of berotralstat for hereditary angioedema: The open-label APeX-S studyHenriette Farkas, Marcin Stobiecki, Jonny Peter, et al.
Lancet (London, England)|February 11, 2023
An investigational oral plasma kallikrein inhibitor for on-demand treatment of hereditary angioedema: a two-part, randomised, double-blind, placebo-controlled, crossover phase 2 trialEmel Aygören-Pürsün, Andrea Zanichelli, Danny M Cohn, et al.
The Lancet. Haematology|March 22, 2026
Oral deucrictibant for prophylaxis of hereditary angioedema attacks (CHAPTER-1): primary analysis of a randomised, double-blind, placebo-controlled, phase 2 trialEmel Aygören-Pürsün, Marcin Stobiecki, Anna Valerieva, et al.
The New England Journal of Medicine|July 26, 2018
Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary AngioedemaEmel Aygören-Pürsün, Anette Bygum, Vesna Grivcheva-Panovska, et al.
The Journal of Allergy and Clinical Immunology. Global|April 25, 2025
Global frequency, diagnosis, and treatment of hereditary angioedema with normal C1 inhibitorMarkus Magerl, Marc A Riedl, Luisa Karla Arruda, et al.
The Journal of Allergy and Clinical Immunology|October 25, 2020
Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: A randomized, double-blind, placebo-controlled phase 3 trialBruce Zuraw, William R Lumry, Douglas T Johnston, et al.
The Journal of Allergy and Clinical Immunology. Global|July 12, 2026
Sebetralstat for breakthrough attacks in patients with hereditary angioedema receiving long-term prophylaxis in KONFIDENT-STamar Kinaciyan, Emel Aygören-Pürsün, Inmaculada Martinez-Saguer, et al.
The Journal of Allergy and Clinical Immunology. in Practice|August 31, 2025
Long-term Safety and Effectiveness of Sebetralstat: Interim Analysis of KONFIDENT-S Open-label ExtensionHenriette Farkas, John Anderson, Laurence Bouillet, et al.
The World Allergy Organization Journal|June 19, 2026
Sebetralstat for on-demand treatment of hereditary angioedema: A pooled analysis of placebo-controlled clinical trialsEmel Aygören-Pürsün, Danny M Cohn, Nancy Agmon-Levin, et al.
The Journal of Allergy and Clinical Immunology. in Practice|April 12, 2024
A Core Outcome Set for Efficacy of Acute Treatment of Hereditary AngioedemaRemy S Petersen, Lauré M Fijen, Christian Apfelbacher, et al.
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