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Bioorganic & Medicinal Chemistry|September 25, 2019
Structure optimization of a new class of PPARγ antagonistsVictor Hernandez-Olmos, Tilo Knape, Jan Heering, et al.
Biochemical Pharmacology|July 30, 2022
Compilation and evaluation of a fatty acid mimetics screening libraryJohanna H M Ehrler, Steffen Brunst, Amelie Tjaden, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|June 27, 2021
Learning from Nature: From a Marine Natural Product to Synthetic Cyclooxygenase-1 Inhibitors by Automated De Novo DesignLukas Friedrich, Gino Cingolani, Ying-Hui Ko, et al.
Bioorganic Chemistry|September 5, 2021
Biological evaluation and synthesis of calcitroic acidOlivia B Yu, Daniel A Webb, Elliot S Di Milo, et al.
Nature Communications|July 4, 2019
Molecular tuning of farnesoid X receptor partial agonismDaniel Merk, Sridhar Sreeramulu, Denis Kudlinzki, et al.
Journal of Medicinal Chemistry|August 29, 2017
A Dual Modulator of Farnesoid X Receptor and Soluble Epoxide Hydrolase To Counter Nonalcoholic SteatohepatitisJurema Schmidt, Marco Rotter, Tim Weiser, et al.
Journal of Medicinal Chemistry|June 8, 2018
Boosting Anti-Inflammatory Potency of Zafirlukast by Designed PolypharmacologySimone Schierle, Cathrin Flauaus, Pascal Heitel, et al.
Journal of Medicinal Chemistry|July 31, 2024
Structural Optimization of Oxaprozin for Selective Inverse Nurr1 AgonismSabine Willems, Romy Busch, Felix Nawa, et al.
Journal of Medicinal Chemistry|April 9, 2020
A Selective Modulator of Peroxisome Proliferator-Activated Receptor γ with an Unprecedented Binding ModeThomas Hanke, Sun-Yee Cheung, Whitney Kilu, et al.
Frontiers in Pharmacology|April 6, 2019
Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γTamara Göbel, Olaf Diehl, Jan Heering, et al.
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