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Chemmedchem|January 18, 2024
Rational design and virtual screening identify mimetics of the RXR agonist valerenic acidLaura Isigkeit, Annette Kärcher, Gustave Adouvi, et al.
Chemmedchem|June 15, 2022
Druggability Evaluation of the Neuron Derived Orphan Receptor (NOR-1) Reveals Inverse NOR-1 AgonistsDaniel Zaienne, Silvia Arifi, Julian A Marschner, et al.
Future Medicinal Chemistry|August 28, 2015
Pirinixic acids: flexible fatty acid mimetics with various biological activitiesDaniel Merk, Martina Zettl, Dieter Steinhilber, et al.
Chemistryopen|October 30, 2019
Synthetic Activators of Cell Migration Designed by Constructive Machine LearningDominique Bruns, Daniel Merk, Karthiga Santhana Kumar, et al.
Pharmacology & Therapeutics|December 3, 2015
Small molecules with anti-inflammatory properties in clinical developmentThomas Hanke, Daniel Merk, Dieter Steinhilber, et al.
Chemmedchem|February 8, 2022
Scaffold Hopping from Amodiaquine to Novel Nurr1 Agonist Chemotypes via Microscale Analogue LibrariesSabine Willems, Marcel Müller, Julia Ohrndorf, et al.
International Journal of Molecular Sciences|October 29, 2020
Chemical Starting Matter for HNF4α Ligand Discovery and ChemogenomicsIsabelle Meijer, Sabine Willems, Xiaomin Ni, et al.
Chemmedchem|May 30, 2019
Computer-Assisted Selective Optimization of Side-Activities-from Cinalukast to a PPARα ModulatorJulius Pollinger, Simone Schierle, Sebastian Neumann, et al.
ACS Pharmacology & Translational Science|April 16, 2021
Differential Therapeutic Effects of FXR Activation, sEH Inhibition, and Dual FXR/sEH Modulation in NASH in Diet-Induced Obese MiceMoritz Helmstädter, Jurema Schmidt, Astrid Kaiser, et al.
ACS Medicinal Chemistry Letters|January 8, 2026
Dual Nurr1/RXR agonism of valerenic acid and synthetic mimetics enables dimer-selective Nurr1 modulationKatharina Scholz, Úrsula López-García, Romy Busch, et al.
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