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Endocrinology|July 28, 2021
The Src-family Kinase Lyn in Immunoreceptor SignalingBen F Brian, Tanya S FreedmanCurrent Protocols in Immunology|September 15, 2020
Immunopharmacology and Quantitative Analysis of Tyrosine Kinase SignalingBen F Brian, Candace R Guerrero, Tanya S FreedmanScientific Reports|April 8, 2022
SH3-domain mutations selectively disrupt Csk homodimerization or PTPN22 bindingBen F Brian, Frances V Sjaastad, Tanya S FreedmanBiorxiv : the Preprint Server for Biology|July 17, 2025
Total, not isoform-specific, Lyn expression by macrophages promotes TLR activation and restricts proliferationAnders J Lindstedt, Joseph T Greene, Tanya S FreedmanBiorxiv : the Preprint Server for Biology|May 13, 2026
Dose-dependent activation of Syk and SHIP1 by LynA and LynB at steady state creates a thresh-old for macrophage signaling in the absence of receptor engagementS Erandika Senevirathne, Carter E Sellner, Silvia Toledo Ramos, et al.Current Opinion in Immunology|October 3, 2021
Regulation of myeloid-cell activationJoseph T Greene, Ben F Brian, S Erandika Senevirathne, et al.Structure (London, England : 1993)|January 15, 2009
Differences in flexibility underlie functional differences in the Ras activators son of sevenless and Ras guanine nucleotide releasing factor 1Tanya S Freedman, Holger Sondermann, Olga Kuchment, et al.Journal of Leukocyte Biology|October 7, 2025
Lyn expression in macrophages promotes TLR activation and restricts proliferation in an isoform-independent mannerAnders J Lindstedt, Joseph T Greene, Yingzheng Xu, et al.Nature Immunology|December 10, 2013
Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signalingYing Xim Tan, Boryana N Manz, Tanya S Freedman, et al.Proceedings of the National Academy of Sciences of the United States of America|November 1, 2006
A Ras-induced conformational switch in the Ras activator Son of sevenlessTanya S Freedman, Holger Sondermann, Gregory D Friedland, et al.Pageof 3