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The Journal of Biological Chemistry|January 22, 2026
Acid ceramidase ASAH1 is a key regulator of epidermal ceramide levels and compositionWakana Nobumoto, Tatsuro Naganuma, Nana Nozaka, et al.The Journal of Investigative Dermatology|November 28, 2017
Decreased Skin Barrier Lipid Acylceramide and Differentiation-Dependent Gene Expression in Ichthyosis Gene Nipal4-Knockout MiceYuichi Honda, Takuya Kitamura, Tatsuro Naganuma, et al.Journal of Lipid Research|May 1, 2020
Catalytic residues, substrate specificity, and role in carbon starvation of the 2-hydroxy FA dioxygenase Mpo1 in yeastKeisuke Mori, Takashi Obara, Naoya Seki, et al.Molecular Vision|December 9, 2010
Hetero-oligomeric interactions of an ELOVL4 mutant protein: implications in the molecular mechanism of Stargardt-3 macular dystrophyAyaka Okuda, Tatsuro Naganuma, Yusuke Ohno, et al.Nature Communications|October 28, 2014
Identification of the phytosphingosine metabolic pathway leading to odd-numbered fatty acidsNatsuki Kondo, Yusuke Ohno, Maki Yamagata, et al.The Journal of Biological Chemistry|April 8, 2016
Disruption of the Sjögren-Larsson Syndrome Gene Aldh3a2 in Mice Increases Keratinocyte Growth and Retards Skin Barrier RecoveryTatsuro Naganuma, Shuyu Takagi, Tsukasa Kanetake, et al.The Journal of Biological Chemistry|March 12, 2023
Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine ceramidesAi Ota, Hiroya Morita, Tatsuro Naganuma, et al.Molecular Cell|May 29, 2012
The Sjögren-Larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathwayKanae Nakahara, Aya Ohkuni, Takuya Kitamura, et al.The Journal of Investigative Dermatology|June 25, 2022
Microbiota-Independent Spontaneous Dermatitis Associated with Increased Sebaceous Lipid Production in Tmem79-Deficient MiceAri Morimoto, Keitaro Fukuda, Yoshihiro Ito, et al.The Journal of Investigative Dermatology|November 1, 2019
Homeostatic Function of Dermokine in the Skin Barrier and InflammationAkira Utsunomiya, Takenao Chino, Natsuko Utsunomiya, et al.Pageof 3