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Journal of Medicinal Chemistry|October 30, 2024
DBPR116, a Prodrug of BPRMU191, in Combination with Naltrexone as a Safer Opioid Analgesic Than Morphine via Peripheral AdministrationShu-Yu Lin, Yung-Chiao Chang, Ya-Wen Tien, et al.Journal of Medicinal Chemistry|October 22, 2010
Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and Michael acceptor group for maximal potencyChia-Hsien Wu, Mohane Selvaraj Coumar, Chang-Ying Chu, et al.Oncotarget|November 19, 2016
Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluationYung Chang Hsu, Mohane Selvaraj Coumar, Wen-Chieh Wang, et al.Bioorganic Chemistry|March 2, 2018
4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacyShu-Yu Lin, Teng-Kuang Yeh, Jen-Shin Song, et al.Journal of Medicinal Chemistry|February 27, 2025
Orally Bioavailable and Site-Selective Covalent STING Inhibitor Derived from a Macrocyclic Marine DiterpenoidGuang-Hao Niu, Wan-Chi Hsiao, Po-Hsun Lee, et al.European Journal of Medicinal Chemistry|December 20, 2021
Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug designTeng-Kuang Yeh, Jen-Shin Song, Po-Wei Chang, et al.Journal of Medicinal Chemistry|November 14, 2019
Identification of a Multitargeted Tyrosine Kinase Inhibitor for the Treatment of Gastrointestinal Stromal Tumors and Acute Myeloid LeukemiaWen-Hsing Lin, Su-Ying Wu, Teng-Kuang Yeh, et al.EMBO Molecular Medicine|March 22, 2025
Identification of PTGR2 inhibitors as a new therapeutic strategy for diabetes and obesityYi-Cheng Chang, Meng-Lun Hsieh, Hsiao-Lin Lee, et al.Pageof 13