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Chemical Science
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May 14, 2025
Discovery and optimisation of a covalent ligand for TRIM25 and its application to targeted protein ubiquitination
Katherine A McPhie, Diego Esposito, Jonathan Pettinger, et al.
ACS Chemical Biology
|
July 8, 2016
A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level
Anna Rutkowska, Douglas W Thomson, Johanna Vappiani, et al.
Nature Biotechnology
|
January 2, 2007
Computational prediction of proteotypic peptides for quantitative proteomics
Parag Mallick, Markus Schirle, Sharon S Chen, et al.
Scientific Reports
|
October 4, 2019
Chemical proteomics reveals target selectivity of clinical Jak inhibitors in human primary cells
H Christian Eberl, Thilo Werner, Friedrich B Reinhard, et al.
Nature Methods
|
November 3, 2015
Thermal proteome profiling monitors ligand interactions with cellular membrane proteins
Friedrich B M Reinhard, Dirk Eberhard, Thilo Werner, et al.
ACS Chemical Biology
|
February 19, 2014
The commonly used PI3-kinase probe LY294002 is an inhibitor of BET bromodomains
Antje Dittmann, Thilo Werner, Chun-Wa Chung, et al.
Journal of the American Chemical Society
|
December 13, 2017
Selectively Targeting the Kinome-Conserved Lysine of PI3Kδ as a General Approach to Covalent Kinase Inhibition
Samuel E Dalton, Lars Dittus, Daniel A Thomas, et al.
Nature Chemical Biology
|
September 27, 2016
Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat
Isabelle Becher, Thilo Werner, Carola Doce, et al.
Nature Protocols
|
September 18, 2015
Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry
Holger Franken, Toby Mathieson, Dorothee Childs, et al.
Journal of Medicinal Chemistry
|
July 22, 2020
GSK789: A Selective Inhibitor of the First Bromodomains (BD1) of the Bromo and Extra Terminal Domain (BET) Proteins
Robert J Watson, Paul Bamborough, Heather Barnett, et al.
Page
of 4
Search research articles
Search
Showing results (11-20 of 39) with videos related to
Sort By:
Page
of 4
Chemical Science
|
May 14, 2025
Discovery and optimisation of a covalent ligand for TRIM25 and its application to targeted protein ubiquitination
Katherine A McPhie, Diego Esposito, Jonathan Pettinger, et al.
ACS Chemical Biology
|
July 8, 2016
A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level
Anna Rutkowska, Douglas W Thomson, Johanna Vappiani, et al.
Nature Biotechnology
|
January 2, 2007
Computational prediction of proteotypic peptides for quantitative proteomics
Parag Mallick, Markus Schirle, Sharon S Chen, et al.
Scientific Reports
|
October 4, 2019
Chemical proteomics reveals target selectivity of clinical Jak inhibitors in human primary cells
H Christian Eberl, Thilo Werner, Friedrich B Reinhard, et al.
Nature Methods
|
November 3, 2015
Thermal proteome profiling monitors ligand interactions with cellular membrane proteins
Friedrich B M Reinhard, Dirk Eberhard, Thilo Werner, et al.
ACS Chemical Biology
|
February 19, 2014
The commonly used PI3-kinase probe LY294002 is an inhibitor of BET bromodomains
Antje Dittmann, Thilo Werner, Chun-Wa Chung, et al.
Journal of the American Chemical Society
|
December 13, 2017
Selectively Targeting the Kinome-Conserved Lysine of PI3Kδ as a General Approach to Covalent Kinase Inhibition
Samuel E Dalton, Lars Dittus, Daniel A Thomas, et al.
Nature Chemical Biology
|
September 27, 2016
Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat
Isabelle Becher, Thilo Werner, Carola Doce, et al.
Nature Protocols
|
September 18, 2015
Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry
Holger Franken, Toby Mathieson, Dorothee Childs, et al.
Journal of Medicinal Chemistry
|
July 22, 2020
GSK789: A Selective Inhibitor of the First Bromodomains (BD1) of the Bromo and Extra Terminal Domain (BET) Proteins
Robert J Watson, Paul Bamborough, Heather Barnett, et al.
Page
of 4