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Thilo Werner

Showing results (21-30 of 39) with videos related to

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Molecular Systems Biology|March 7, 2024
Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibitionMira L Burtscher, Stephan Gade, Martin Garrido-Rodriguez, et al.
Science (New York, N.Y.)|October 4, 2014
Tracking cancer drugs in living cells by thermal profiling of the proteomeMikhail M Savitski, Friedrich B M Reinhard, Holger Franken, et al.
Journal of Medicinal Chemistry|September 19, 2018
Aiming to Miss a Moving Target: Bromo and Extra Terminal Domain (BET) Selectivity in Constrained ATAD2 InhibitorsPaul Bamborough, Chun-Wa Chung, Rebecca C Furze, et al.
Journal of Medicinal Chemistry|March 24, 2015
Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2BPeiling Chen, Apirat Chaikuad, Paul Bamborough, et al.
Journal of Medicinal Chemistry|August 1, 2015
Structure-Based Optimization of Naphthyridones into Potent ATAD2 Bromodomain InhibitorsPaul Bamborough, Chun-wa Chung, Rebecca C Furze, et al.
Journal of Medicinal Chemistry|May 16, 2020
Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) BromodomainsMichael A Clegg, Paul Bamborough, Chun-Wa Chung, et al.
Journal of Medicinal Chemistry|January 9, 2025
Phenotype-Led Identification of IL-10 Upregulators in Human CD4<sup>+</sup> T-cells and Elucidation of Their Pharmacology as Highly Selective CDK8/CDK19 InhibitorsSimon Nicolle, Mike Barker, John Barrett, et al.
Nature Chemical Biology|May 1, 2012
A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiationGiovanna Bergamini, Kathryn Bell, Satoko Shimamura, et al.
Science Advances|May 27, 2021
BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translationZlata Vershinin, Michal Feldman, Thilo Werner, et al.
Nature Methods|April 15, 2020
Meltome atlas-thermal proteome stability across the tree of lifeAnna Jarzab, Nils Kurzawa, Thomas Hopf, et al.
Pageof 4

Showing results (21-30 of 39) with videos related to

Sort By:
Pageof 4
Molecular Systems Biology|March 7, 2024
Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibitionMira L Burtscher, Stephan Gade, Martin Garrido-Rodriguez, et al.
Science (New York, N.Y.)|October 4, 2014
Tracking cancer drugs in living cells by thermal profiling of the proteomeMikhail M Savitski, Friedrich B M Reinhard, Holger Franken, et al.
Journal of Medicinal Chemistry|September 19, 2018
Aiming to Miss a Moving Target: Bromo and Extra Terminal Domain (BET) Selectivity in Constrained ATAD2 InhibitorsPaul Bamborough, Chun-Wa Chung, Rebecca C Furze, et al.
Journal of Medicinal Chemistry|March 24, 2015
Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2BPeiling Chen, Apirat Chaikuad, Paul Bamborough, et al.
Journal of Medicinal Chemistry|August 1, 2015
Structure-Based Optimization of Naphthyridones into Potent ATAD2 Bromodomain InhibitorsPaul Bamborough, Chun-wa Chung, Rebecca C Furze, et al.
Journal of Medicinal Chemistry|May 16, 2020
Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) BromodomainsMichael A Clegg, Paul Bamborough, Chun-Wa Chung, et al.
Journal of Medicinal Chemistry|January 9, 2025
Phenotype-Led Identification of IL-10 Upregulators in Human CD4<sup>+</sup> T-cells and Elucidation of Their Pharmacology as Highly Selective CDK8/CDK19 InhibitorsSimon Nicolle, Mike Barker, John Barrett, et al.
Nature Chemical Biology|May 1, 2012
A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiationGiovanna Bergamini, Kathryn Bell, Satoko Shimamura, et al.
Science Advances|May 27, 2021
BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translationZlata Vershinin, Michal Feldman, Thilo Werner, et al.
Nature Methods|April 15, 2020
Meltome atlas-thermal proteome stability across the tree of lifeAnna Jarzab, Nils Kurzawa, Thomas Hopf, et al.
Pageof 4