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Thomas A Keating

Showing results (11-20 of 29) with videos related to

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Antimicrobial Agents and Chemotherapy|April 1, 2015
In vitro activity of ceftazidime-avibactam against 338 molecularly characterized gentamicin-nonsusceptible Gram-negative clinical isolates obtained from patients in Canadian hospitalsAndrew J Denisuik, James A Karlowsky, Tyler Denisuik, et al.
The Journal of Biological Chemistry|October 11, 2011
In vitro validation of acetyltransferase activity of GlmU as an antibacterial target in Haemophilus influenzaeEd T Buurman, Beth Andrews, Ning Gao, et al.
Nature|June 15, 2007
Exploitation of structural and regulatory diversity in glutamate racemasesTomas Lundqvist, Stewart L Fisher, Gunther Kern, et al.
Neoplasia (New York, N.Y.)|January 1, 2021
Quantifying ADC bystander payload penetration with cellular resolution using pharmacodynamic mappingEshita Khera, Cornelius Cilliers, Michael D Smith, et al.
Cancer Research|January 17, 2020
Increased Tumor Penetration of Single-Domain Antibody-Drug Conjugates Improves <i>In Vivo</i> Efficacy in Prostate Cancer ModelsIan Nessler, Eshita Khera, Steven Vance, et al.
Molecular Pharmaceutics|October 15, 2019
Optimizing Lysosomal Activation of Antibody-Drug Conjugates (ADCs) by Incorporation of Novel Cleavable Dipeptide LinkersPaulin L Salomon, Emily E Reid, Katie E Archer, et al.
Molecular Cancer Therapeutics|November 12, 2020
Antibody Co-Administration Can Improve Systemic and Local Distribution of Antibody-Drug Conjugates to Increase <i>In Vivo</i> EfficacyJose F Ponte, Leanne Lanieri, Eshita Khera, et al.
Bioconjugate Chemistry|November 21, 2019
Site-Specific Conjugation of the Indolinobenzodiazepine DGN549 to Antibodies Affords Antibody-Drug Conjugates with an Improved Therapeutic Index as Compared with Lysine ConjugationChen Bai, Emily E Reid, Alan Wilhelm, et al.
Journal of Medicinal Chemistry|May 16, 2014
Antibacterial inhibitors of Gram-positive thymidylate kinase: structure-activity relationships and chiral preference of a new hydrophobic binding regionSameer P Kawatkar, Thomas A Keating, Nelson B Olivier, et al.
Bioconjugate Chemistry|May 14, 2016
Understanding How the Stability of the Thiol-Maleimide Linkage Impacts the Pharmacokinetics of Lysine-Linked Antibody-Maytansinoid ConjugatesJose F Ponte, Xiuxia Sun, Nicholas C Yoder, et al.
Pageof 3

Showing results (11-20 of 29) with videos related to

Sort By:
Pageof 3
Antimicrobial Agents and Chemotherapy|April 1, 2015
In vitro activity of ceftazidime-avibactam against 338 molecularly characterized gentamicin-nonsusceptible Gram-negative clinical isolates obtained from patients in Canadian hospitalsAndrew J Denisuik, James A Karlowsky, Tyler Denisuik, et al.
The Journal of Biological Chemistry|October 11, 2011
In vitro validation of acetyltransferase activity of GlmU as an antibacterial target in Haemophilus influenzaeEd T Buurman, Beth Andrews, Ning Gao, et al.
Nature|June 15, 2007
Exploitation of structural and regulatory diversity in glutamate racemasesTomas Lundqvist, Stewart L Fisher, Gunther Kern, et al.
Neoplasia (New York, N.Y.)|January 1, 2021
Quantifying ADC bystander payload penetration with cellular resolution using pharmacodynamic mappingEshita Khera, Cornelius Cilliers, Michael D Smith, et al.
Cancer Research|January 17, 2020
Increased Tumor Penetration of Single-Domain Antibody-Drug Conjugates Improves <i>In Vivo</i> Efficacy in Prostate Cancer ModelsIan Nessler, Eshita Khera, Steven Vance, et al.
Molecular Pharmaceutics|October 15, 2019
Optimizing Lysosomal Activation of Antibody-Drug Conjugates (ADCs) by Incorporation of Novel Cleavable Dipeptide LinkersPaulin L Salomon, Emily E Reid, Katie E Archer, et al.
Molecular Cancer Therapeutics|November 12, 2020
Antibody Co-Administration Can Improve Systemic and Local Distribution of Antibody-Drug Conjugates to Increase <i>In Vivo</i> EfficacyJose F Ponte, Leanne Lanieri, Eshita Khera, et al.
Bioconjugate Chemistry|November 21, 2019
Site-Specific Conjugation of the Indolinobenzodiazepine DGN549 to Antibodies Affords Antibody-Drug Conjugates with an Improved Therapeutic Index as Compared with Lysine ConjugationChen Bai, Emily E Reid, Alan Wilhelm, et al.
Journal of Medicinal Chemistry|May 16, 2014
Antibacterial inhibitors of Gram-positive thymidylate kinase: structure-activity relationships and chiral preference of a new hydrophobic binding regionSameer P Kawatkar, Thomas A Keating, Nelson B Olivier, et al.
Bioconjugate Chemistry|May 14, 2016
Understanding How the Stability of the Thiol-Maleimide Linkage Impacts the Pharmacokinetics of Lysine-Linked Antibody-Maytansinoid ConjugatesJose F Ponte, Xiuxia Sun, Nicholas C Yoder, et al.
Pageof 3