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ACS Medicinal Chemistry Letters
|
August 16, 2019
Synthesis of Highly Potent N-10 Amino-Linked DNA-Alkylating Indolinobenzodiazepine Antibody-Drug Conjugates (ADCs)
Katie E Archer, Emily E Reid, Manami Shizuka, et al.
Molecular Pharmaceutics
|
July 10, 2019
A Case Study Comparing Heterogeneous Lysine- and Site-Specific Cysteine-Conjugated Maytansinoid Antibody-Drug Conjugates (ADCs) Illustrates the Benefits of Lysine Conjugation
Nicholas C Yoder, Chen Bai, Daniel Tavares, et al.
ACS Medicinal Chemistry Letters
|
October 18, 2019
Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates
Wei Li, Karen H Veale, Qifeng Qiu, et al.
Bioconjugate Chemistry
|
April 9, 2017
Effects of Drug-Antibody Ratio on Pharmacokinetics, Biodistribution, Efficacy, and Tolerability of Antibody-Maytansinoid Conjugates
Xiuxia Sun, Jose F Ponte, Nicholas C Yoder, et al.
Molecular Cancer Therapeutics
|
August 14, 2020
Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody-Drug Conjugate in Patient-derived Xenografts
Adnan O Abu-Yousif, Donna Cvet, Melissa Gallery, et al.
Molecular Cancer Therapeutics
|
February 15, 2018
A DNA-Interacting Payload Designed to Eliminate Cross-Linking Improves the Therapeutic Index of Antibody-Drug Conjugates (ADCs)
Michael L Miller, Manami Shizuka, Alan Wilhelm, et al.
ACS Chemical Biology
|
August 23, 2012
In vivo validation of thymidylate kinase (TMK) with a rationally designed, selective antibacterial compound
Thomas A Keating, Joseph V Newman, Nelson B Olivier, et al.
Journal of Medicinal Chemistry
|
October 10, 2012
Discovery of selective and potent inhibitors of gram-positive bacterial thymidylate kinase (TMK)
Gabriel Martínez-Botella, John N Breen, James E S Duffy, et al.
Nature
|
April 9, 2025
Small molecules restore mutant mitochondrial DNA polymerase activity
Sebastian Valenzuela, Xuefeng Zhu, Bertil Macao, et al.
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Showing results (21-30 of 29) with videos related to
Sort By:
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You have reached the last page of results.
This site can display upto 29 results.
ACS Medicinal Chemistry Letters
|
August 16, 2019
Synthesis of Highly Potent N-10 Amino-Linked DNA-Alkylating Indolinobenzodiazepine Antibody-Drug Conjugates (ADCs)
Katie E Archer, Emily E Reid, Manami Shizuka, et al.
Molecular Pharmaceutics
|
July 10, 2019
A Case Study Comparing Heterogeneous Lysine- and Site-Specific Cysteine-Conjugated Maytansinoid Antibody-Drug Conjugates (ADCs) Illustrates the Benefits of Lysine Conjugation
Nicholas C Yoder, Chen Bai, Daniel Tavares, et al.
ACS Medicinal Chemistry Letters
|
October 18, 2019
Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates
Wei Li, Karen H Veale, Qifeng Qiu, et al.
Bioconjugate Chemistry
|
April 9, 2017
Effects of Drug-Antibody Ratio on Pharmacokinetics, Biodistribution, Efficacy, and Tolerability of Antibody-Maytansinoid Conjugates
Xiuxia Sun, Jose F Ponte, Nicholas C Yoder, et al.
Molecular Cancer Therapeutics
|
August 14, 2020
Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody-Drug Conjugate in Patient-derived Xenografts
Adnan O Abu-Yousif, Donna Cvet, Melissa Gallery, et al.
Molecular Cancer Therapeutics
|
February 15, 2018
A DNA-Interacting Payload Designed to Eliminate Cross-Linking Improves the Therapeutic Index of Antibody-Drug Conjugates (ADCs)
Michael L Miller, Manami Shizuka, Alan Wilhelm, et al.
ACS Chemical Biology
|
August 23, 2012
In vivo validation of thymidylate kinase (TMK) with a rationally designed, selective antibacterial compound
Thomas A Keating, Joseph V Newman, Nelson B Olivier, et al.
Journal of Medicinal Chemistry
|
October 10, 2012
Discovery of selective and potent inhibitors of gram-positive bacterial thymidylate kinase (TMK)
Gabriel Martínez-Botella, John N Breen, James E S Duffy, et al.
Nature
|
April 9, 2025
Small molecules restore mutant mitochondrial DNA polymerase activity
Sebastian Valenzuela, Xuefeng Zhu, Bertil Macao, et al.
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of 3