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Biochemistry
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January 17, 2018
Catalytic Mechanism of Cruzain from Trypanosoma cruzi As Determined from Solvent Kinetic Isotope Effects of Steady-State and Pre-Steady-State Kinetics
Xiang Zhai, Thomas D Meek
Biochemistry
|
August 10, 2019
Enhanced Antibiotic Discovery by PROSPECTing
Vern L Schramm, Thomas D Meek
Plos Neglected Tropical Diseases
|
February 1, 2022
Characterization of adenine phosphoribosyltransferase (APRT) activity in Trypanosoma brucei brucei: Only one of the two isoforms is kinetically active
Kayla Glockzin, Thomas D Meek, Ardala Katzfuss
The Journal of Pharmacology and Experimental Therapeutics
|
November 4, 2020
Inhibiting Sialidase-Induced TGF-<i>β</i>1 Activation Attenuates Pulmonary Fibrosis in Mice
Tejas R Karhadkar, Thomas D Meek, Richard H Gomer
Nature Reviews. Drug Discovery
|
December 2, 2017
Mechanistic enzymology in drug discovery: a fresh perspective
Geoffrey A Holdgate, Thomas D Meek, Rachel L Grimley
Nature Reviews. Drug Discovery
|
August 5, 2006
Drug-target residence time and its implications for lead optimization
Robert A Copeland, David L Pompliano, Thomas D Meek
Nature Reviews. Drug Discovery
|
December 16, 2017
Mechanistic enzymology in drug discovery: a fresh perspective
Geoffrey A Holdgate, Thomas D Meek, Rachel L Grimley
Biochemistry
|
December 14, 2005
Kinetic and chemical mechanisms of the fabG-encoded Streptococcus pneumoniae beta-ketoacyl-ACP reductase
Mehul P Patel, Wu-Schyong Liu, Joshua West, et al.
Biochemistry
|
July 29, 2008
Chemical mechanism of a cysteine protease, cathepsin C, as revealed by integration of both steady-state and pre-steady-state solvent kinetic isotope effects
Jessica L Schneck, James P Villa, Patrick McDevitt, et al.
ACS Catalysis
|
December 26, 2024
Catalytic Mechanism of SARS-CoV-2 3-Chymotrypsin-Like Protease as Determined by Steady-State and Pre-Steady-State Kinetics
Jiyun Zhu, Alexandria M Kemp, Bala C Chenna, et al.
Page
of 4
Search research articles
Search
Showing results (1-10 of 36) with videos related to
Sort By:
Page
of 4
Biochemistry
|
January 17, 2018
Catalytic Mechanism of Cruzain from Trypanosoma cruzi As Determined from Solvent Kinetic Isotope Effects of Steady-State and Pre-Steady-State Kinetics
Xiang Zhai, Thomas D Meek
Biochemistry
|
August 10, 2019
Enhanced Antibiotic Discovery by PROSPECTing
Vern L Schramm, Thomas D Meek
Plos Neglected Tropical Diseases
|
February 1, 2022
Characterization of adenine phosphoribosyltransferase (APRT) activity in Trypanosoma brucei brucei: Only one of the two isoforms is kinetically active
Kayla Glockzin, Thomas D Meek, Ardala Katzfuss
The Journal of Pharmacology and Experimental Therapeutics
|
November 4, 2020
Inhibiting Sialidase-Induced TGF-<i>β</i>1 Activation Attenuates Pulmonary Fibrosis in Mice
Tejas R Karhadkar, Thomas D Meek, Richard H Gomer
Nature Reviews. Drug Discovery
|
December 2, 2017
Mechanistic enzymology in drug discovery: a fresh perspective
Geoffrey A Holdgate, Thomas D Meek, Rachel L Grimley
Nature Reviews. Drug Discovery
|
August 5, 2006
Drug-target residence time and its implications for lead optimization
Robert A Copeland, David L Pompliano, Thomas D Meek
Nature Reviews. Drug Discovery
|
December 16, 2017
Mechanistic enzymology in drug discovery: a fresh perspective
Geoffrey A Holdgate, Thomas D Meek, Rachel L Grimley
Biochemistry
|
December 14, 2005
Kinetic and chemical mechanisms of the fabG-encoded Streptococcus pneumoniae beta-ketoacyl-ACP reductase
Mehul P Patel, Wu-Schyong Liu, Joshua West, et al.
Biochemistry
|
July 29, 2008
Chemical mechanism of a cysteine protease, cathepsin C, as revealed by integration of both steady-state and pre-steady-state solvent kinetic isotope effects
Jessica L Schneck, James P Villa, Patrick McDevitt, et al.
ACS Catalysis
|
December 26, 2024
Catalytic Mechanism of SARS-CoV-2 3-Chymotrypsin-Like Protease as Determined by Steady-State and Pre-Steady-State Kinetics
Jiyun Zhu, Alexandria M Kemp, Bala C Chenna, et al.
Page
of 4