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Thomas D Penning

Showing results (21-30 of 34) with videos related to

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Bioorganic & Medicinal Chemistry Letters|November 7, 2002
Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolaseThomas D Penning, Nizal S Chandrakumar, Bipin N Desai, et al.
ACS Medicinal Chemistry Letters|July 16, 2021
Balancing Properties with Carboxylates: A Lead Optimization Campaign for Selective and Orally Active CDK9 InhibitorsYunsong Tong, Alan S Florjancic, Rick F Clark, et al.
Bioorganic & Medicinal Chemistry Letters|March 20, 2003
Synthesis of imidazopyridines and purines as potent inhibitors of leukotriene A4 hydrolaseThomas D Penning, Nizal S Chandrakumar, Bipin N Desai, et al.
Journal of Medicinal Chemistry|July 26, 2002
Synthesis of potent leukotriene A(4) hydrolase inhibitors. Identification of 3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acidThomas D Penning, Mark A Russell, Barbara B Chen, et al.
Anticancer Research|November 28, 2008
The PARP inhibitor, ABT-888 potentiates temozolomide: correlation with drug levels and reduction in PARP activity in vivoJoann P Palma, Luis E Rodriguez, Velitchka D Bontcheva-Diaz, et al.
Bioorganic & Medicinal Chemistry Letters|November 24, 2005
Synthesis of 2,5-thiazole butanoic acids as potent and selective alpha(v)beta3 integrin receptor antagonists with improved oral pharmacokinetic propertiesJohn A Wendt, Hongwei Wu, Heather G Stenmark, et al.
Bioorganic & Medicinal Chemistry Letters|April 20, 2006
Synthesis of pyrazoles and isoxazoles as potent alpha(v)beta3 receptor antagonistsThomas D Penning, Albert Khilevich, Barbara B Chen, et al.
Journal of Medicinal Chemistry|March 27, 2010
Optimization of phenyl-substituted benzimidazole carboxamide poly(ADP-ribose) polymerase inhibitors: identification of (S)-2-(2-fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a highly potent and efficacious inhibitorThomas D Penning, Gui-Dong Zhu, Jianchun Gong, et al.
Bioorganic & Medicinal Chemistry|June 11, 2008
Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancerThomas D Penning, Gui-Dong Zhu, Viraj B Gandhi, et al.
Journal of Medicinal Chemistry|May 26, 2007
Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase B/Akt inhibitors with reduced hypotensionGui-Dong Zhu, Viraj B Gandhi, Jianchun Gong, et al.
Pageof 4

Showing results (21-30 of 34) with videos related to

Sort By:
Pageof 4
Bioorganic & Medicinal Chemistry Letters|November 7, 2002
Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolaseThomas D Penning, Nizal S Chandrakumar, Bipin N Desai, et al.
ACS Medicinal Chemistry Letters|July 16, 2021
Balancing Properties with Carboxylates: A Lead Optimization Campaign for Selective and Orally Active CDK9 InhibitorsYunsong Tong, Alan S Florjancic, Rick F Clark, et al.
Bioorganic & Medicinal Chemistry Letters|March 20, 2003
Synthesis of imidazopyridines and purines as potent inhibitors of leukotriene A4 hydrolaseThomas D Penning, Nizal S Chandrakumar, Bipin N Desai, et al.
Journal of Medicinal Chemistry|July 26, 2002
Synthesis of potent leukotriene A(4) hydrolase inhibitors. Identification of 3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acidThomas D Penning, Mark A Russell, Barbara B Chen, et al.
Anticancer Research|November 28, 2008
The PARP inhibitor, ABT-888 potentiates temozolomide: correlation with drug levels and reduction in PARP activity in vivoJoann P Palma, Luis E Rodriguez, Velitchka D Bontcheva-Diaz, et al.
Bioorganic & Medicinal Chemistry Letters|November 24, 2005
Synthesis of 2,5-thiazole butanoic acids as potent and selective alpha(v)beta3 integrin receptor antagonists with improved oral pharmacokinetic propertiesJohn A Wendt, Hongwei Wu, Heather G Stenmark, et al.
Bioorganic & Medicinal Chemistry Letters|April 20, 2006
Synthesis of pyrazoles and isoxazoles as potent alpha(v)beta3 receptor antagonistsThomas D Penning, Albert Khilevich, Barbara B Chen, et al.
Journal of Medicinal Chemistry|March 27, 2010
Optimization of phenyl-substituted benzimidazole carboxamide poly(ADP-ribose) polymerase inhibitors: identification of (S)-2-(2-fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a highly potent and efficacious inhibitorThomas D Penning, Gui-Dong Zhu, Jianchun Gong, et al.
Bioorganic & Medicinal Chemistry|June 11, 2008
Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancerThomas D Penning, Gui-Dong Zhu, Viraj B Gandhi, et al.
Journal of Medicinal Chemistry|May 26, 2007
Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase B/Akt inhibitors with reduced hypotensionGui-Dong Zhu, Viraj B Gandhi, Jianchun Gong, et al.
Pageof 4