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Antimicrobial Agents and Chemotherapy|March 10, 2022
An Optimized Dihydrodibenzothiazepine Lead Compound (SBI-0797750) as a Potent and Selective Inhibitor of Plasmodium falciparum and P. vivax Glucose 6-Phosphate Dehydrogenase 6-PhosphogluconolactonaseIsabell Berneburg, Satyamaheshwar Peddibhotla, Kim C Heimsch, et al.
Cancer Letters|February 17, 2019
Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cellsYongmei Feng, E Hampton Sessions, Fan Zhang, et al.
Nature Chemical Biology|March 1, 2017
Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11Jing Li, Tanya Yakushi, Francesco Parlati, et al.
Biorxiv : the Preprint Server for Biology|May 25, 2026
Small-molecule modulators of HIPK4 activity and proteostasisZaile Zhuang, Riley K Togashi, Patrick Kearney, et al.
Bioorganic & Medicinal Chemistry Letters|September 27, 2012
Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptorPatrick R Maloney, Pasha Khan, Michael Hedrick, et al.
Nature Chemical Biology|March 28, 2017
Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphataseStephanie M Stanford, Alexander E Aleshin, Vida Zhang, et al.
Bioorganic & Medicinal Chemistry Letters|January 14, 2014
Identification of a selective inhibitor of murine intestinal alkaline phosphatase (ML260) by concurrent ultra-high throughput screening against human and mouse isozymesRobert J Ardecky, Ekaterina V Bobkova, Tina Kiffer-Moreira, et al.
Journal of Medicinal Chemistry|July 21, 2012
Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitroJanina Preuss, Patrick Maloney, Satyamaheshwar Peddibhotla, et al.
ACS Chemical Neuroscience|June 28, 2012
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement StrategyKevin J Frankowski, Michael P Hedrick, Palak Gosalia, et al.
Circulation|December 19, 2014
Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosisLucia Musumeci, Marijke J Kuijpers, Karen Gilio, et al.
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